# How To Slow Down Aging By Getting Uncomfortable | David Sinclair

Page: https://stenobird.com/podcast/the-daily-motivation-5671643/how-to-slow-down-aging-by-getting-uncomfortable-david-sinclair
Text version: https://stenobird.com/podcast/the-daily-motivation-5671643/how-to-slow-down-aging-by-getting-uncomfortable-david-sinclair.md
Podcast: [The Daily Motivation](https://stenobird.com/podcast/the-daily-motivation-5671643)
Published: 2026-08-01T07:00:00+00:00
Episode link: https://lewishowes.com/podcast/live-a-longer-life-and-reverse-aging-with-dr-david-sinclair/
Audio file: https://pdst.fm/e/stitcher.simplecastaudio.com/c15f81c9-8d65-4cd9-b8dc-49f981d5a9e4/episodes/b9e00768-83ce-479c-a10b-bbde4721af64/audio/128/default.mp3?aid=rss_feed&awCollectionId=c15f81c9-8d65-4cd9-b8dc-49f981d5a9e4&awEpisodeId=b9e00768-83ce-479c-a10b-bbde4721af64&feed=fFPK3rs_
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JSON: https://stenobird.com/v1/public/podcasts/the-daily-motivation-5671643/episodes/how-to-slow-down-aging-by-getting-uncomfortable-david-sinclair
Duration seconds: 447

## Resource

Harvard geneticist David Sinclair tells Lewis Howes why comfort might be the biggest threat to a long life, revealing how cold, fasting, and controlled stress trigger the body's own anti-aging defenses. From calorie-restricted mice that stay young for years to Lewis's own freezing mountain hike, this conversation shows why getting a little uncomfortable on purpose could add decades to your life.

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## Transcript

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