# Episode 156 - Rafiq Hasan - CEO of Complement Therapeutics

Page: https://stenobird.com/podcast/the-biohub-by-avetix-7252289/episode-156-rafiq-hasan-ceo-of-complement-therapeutics
Text version: https://stenobird.com/podcast/the-biohub-by-avetix-7252289/episode-156-rafiq-hasan-ceo-of-complement-therapeutics.md
Podcast: [The BioHub - by Avetix](https://stenobird.com/podcast/the-biohub-by-avetix-7252289)
Published: 2026-04-21T07:48:01+00:00
Episode link: https://podcasters.spotify.com/pod/show/max-brennan4/episodes/Episode-156---Rafiq-Hasan---CEO-of-Complement-Therapeutics-e3i7ha1
Audio file: https://anchor.fm/s/f0076084/podcast/play/118784769/https%3A%2F%2Fd3ctxlq1ktw2nl.cloudfront.net%2Fstaging%2F2026-3-21%2F422507405-44100-2-0ca06f96e1165.mp3
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JSON: https://stenobird.com/v1/public/podcasts/the-biohub-by-avetix-7252289/episodes/episode-156-rafiq-hasan-ceo-of-complement-therapeutics
Duration seconds: 1259

## Resource

We sit down with Rafiq Hasan, co-founder & CEO of Complement Therapeutics, at their London offices to unpack a milestone-loaded past 6 months. Rafiq shares the company's thesis, based on research from Manchester university, and how in practice they are targeting the complement system. We also dig into a landmark moment for the company - the recent dosing of patients in OPTI-GAIN, their Phase 1/2 clinical trial targeting Geographic Atrophy, a leading cause of irreversible vision loss. Another topic of discussion centers around what it's took to build a biotech from the ground up over the past few challenging years. Definitely worth a listen for anyone building in ophthalmology, gene therapy, or across UK biotech.

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## Transcript

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