# A Strategic Turn from Obesity to Cancer

Page: https://stenobird.com/podcast/the-bio-report-1092382/a-strategic-turn-from-obesity-to-cancer
Text version: https://stenobird.com/podcast/the-bio-report-1092382/a-strategic-turn-from-obesity-to-cancer.md
Podcast: [The Bio Report](https://stenobird.com/podcast/the-bio-report-1092382)
Published: 2026-02-18T08:00:00+00:00
Episode link: https://thebioreport.podbean.com/e/a-strategic-turn-from-obesity-to-cancer/
Audio file: https://mcdn.podbean.com/mf/web/26b77zys8m8dq3ih/BR-Amy_Burroughs-2-19-267rayx.mp3
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JSON: https://stenobird.com/v1/public/podcasts/the-bio-report-1092382/episodes/a-strategic-turn-from-obesity-to-cancer
Duration seconds: 1373

## Resource

When Amy Burroughs stepped in as CEO of Terns Pharmaceuticals, she not only had to fill a void created by the death of her predecessor, but also lead a strategic shift from an increasingly crowded area of metabolic disease to focus on its experimental therapy for chronic myeloid leukemia. The company’s allosteric BCR-ABL inhibitor binds to a different site on the fusion protein than most first- and second-generation tyrosine kinase inhibitors. The data have the company and its investors believing the drug can reset the bar for both efficacy and tolerability in a multibillion-dollar market. We spoke with Burroughs about reinventing the company, the decision to seek partners for non-core assets, and how she is charting a clear path toward a broader oncology future.

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## Transcript

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