# RAS breakthrough in pancreatic cancer & Personalized mRNA vaccine for melanoma - News (Jun 2, 2026)

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Podcast: [The Automated Daily](https://stenobird.com/podcast/the-automated-daily-6466996)
Published: 2026-06-02T16:44:49+00:00
Episode link: https://theautomateddaily.com/episodes/2026-06-02-ras-breakthrough-in-pancreatic-cancer-personalized-mrna-vaccine-for-melanoma
Audio file: https://dts.podtrac.com/redirect.mp3/cdn.theautomateddaily.com/audio/news/2026-06-02/en/episode.mp3
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JSON: https://stenobird.com/v1/public/podcasts/the-automated-daily-6466996/episodes/ras-breakthrough-in-pancreatic-cancer-personalized-mrna-vaccine-for-melanoma-news-jun-2-2026
Duration seconds: 427

## Resource

Please support this podcast by checking out our sponsors: - SurveyMonkey, Using AI to surface insights faster and reduce manual analysis time - https://get.surveymonkey.com/tad - Consensus: AI for Research. Get a free month - https://get.consensus.app/automated_daily - Invest Like the Pros with StockMVP - https://www.stock-mvp.com/?via=ron Support The Automated Daily directly: Buy me a coffee: https://buymeacoffee.com/theautomateddaily Today's topics: RAS breakthrough in pancreatic cancer - A major clinical trial reports daraxonrasib, a broad RAS inhibitor, nearly doubled median survival in advanced pancreatic cancer—challenging the long-held “undruggable” RAS narrative and boosting combination-therapy hopes. Personalized mRNA vaccine for melanoma - Five-year data suggest a personalized mRNA cancer vaccine plus Keytruda lowers melanoma recurrence risk and improves overall survival, strengthening the case for mRNA, neoantigens, and tailored immunotherapy in high-risk patients. New options for hard-to-treat cancers - Several oncology updates point to fresh approaches for resistant disease: an immune-escape ‘smart drug’ showing early promise, strong responses to injectable amivantamab in recurrent head and neck cancer, and improved surgical outcomes in high-risk prostate cancer. Ultrasound sticker pacemaker research - MIT-led researchers tested a noninvasive pacemaker concept: a small chest sticker delivering ultrasound pulses to regulate heart rhythm, hinting at future surgery-free pacing and closed-loop wearable cardiac care. Maternal health crisis in CAR camps - A report from a refugee camp near Birao describes women giving birth without transport, staff, or supplies as humanitarian funding cuts deepen a maternal mortality emergency in conflict-hit Central African Repu…

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