# #149 | Mini-Brains in Space | Prof. Alysson Muotri, UC San Diego Page: https://stenobird.com/podcast/space-business-podcast-274990/149-mini-brains-in-space-prof-alysson-muotri-uc-san-diego Text version: https://stenobird.com/podcast/space-business-podcast-274990/149-mini-brains-in-space-prof-alysson-muotri-uc-san-diego.md Podcast: [Space Business Podcast](https://stenobird.com/podcast/space-business-podcast-274990) Published: 2025-07-28T11:41:09+00:00 Episode link: https://spacebusiness.podbean.com/e/149-mini-brains-in-space-prof-alysson-muotri-uc-san-diego/ Audio file: https://mcdn.podbean.com/mf/web/pk3qa2fzbp4uqigx/Copy_of_sbp_AlyssonMuotri_audio_edited91iyj.mp3 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/space-business-podcast-274990/episodes/149-mini-brains-in-space-prof-alysson-muotri-uc-san-diego Duration seconds: 2994 ## Resource Mini-brains in space. Did you know that we can study something called brain organoids, effectively mini-brains, in the special conditions in space, on the International Space Station, and that such studies may help us with diseases like Alzheimers, Autism or Parkinsons? My guest this week is Prof. Alysson Muotri from the University of California San Diego. He and his team have flown such brain organoids to the ISS many times already. Don’t miss this episode on what I consider one of the most exciting intersections of space and biology, and ultimately a potential source of massive positive impact right here on Earth! 🕰️ Timestamps: 00:00 Intro00:29 Alysson Muotri02:12 Understanding Brain Organoids03:49 Stem Cells and Brain Organoids10:31 Accelerated Aging in Space14:18 Challenges and Discoveries in Space Research17:33 Applications and Future Research26:43 Neurodegenerative Diseases27:27 Brain Organoids in Computing29:25 Ethical Considerations of Brain Organoids31:32 Regenerative Medicine and Brain Organoids34:39 Brain Evolution and Neanderthal Genes39:21 Space Research and Future Prospects43:58 Challenges and Opportunities in Space Biology47:22 Science-Fiction 🔗 UCSD Sanford Integrated Space Stem Cell Orbital Research Center (ISSCOR) 🏠Website : https://stemcells.ucsd.edu/centers/sanford-integrated-space-stem-cell-orbital-research-center/index.html 🔗 Follow us: 🏠Website : https://www.e2mc.space/ 🤝🏻LinkedIn : https://www.linkedin.com/company/space-business-podcast/ 🌐Socials: https://linktr.ee/spacebusinesspodcast 🔗 Follow Raphael: 🔷LinkedIn - https://www.linkedin.com/in/raphaelroettgen 🌐Instagram - https://instagram.com/raphael_space/ ◇ Twitter/X - https://x.com/RaphaelE2MC To Learn more about Space & the Space Economy: "To Infinity" – Raphael’s Revised Introduction t… ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/space-business-podcast-274990/episodes/149-mini-brains-in-space-prof-alysson-muotri-uc-san-diego/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/space-business-podcast-274990/149-mini-brains-in-space-prof-alysson-muotri-uc-san-diego.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.