# 310. The Fatigue Resistance Episode! Rachel Entrekin Makes History at Cocodona, Women v. Men Durability, Fueling and the Central Nervous System, Brain Changes, and More Page: https://stenobird.com/podcast/some-work-all-play-150821/310-the-fatigue-resistance-episode-rachel-entrekin-makes-history-at-cocodona-women-v-men-durability-fueling-and-the-central-nervous-system-brain-changes-and-more Text version: https://stenobird.com/podcast/some-work-all-play-150821/310-the-fatigue-resistance-episode-rachel-entrekin-makes-history-at-cocodona-women-v-men-durability-fueling-and-the-central-nervous-system-brain-changes-and-more.md Podcast: [Some Work, All Play](https://stenobird.com/podcast/some-work-all-play-150821) Published: 2026-05-12T11:54:16+00:00 Episode link: https://podcasters.spotify.com/pod/show/someworkallplay/episodes/310--The-Fatigue-Resistance-Episode--Rachel-Entrekin-Makes-History-at-Cocodona--Women-v--Men-Durability--Fueling-and-the-Central-Nervous-System--Brain-Changes--and-More-e3j8mt4 Audio file: https://anchor.fm/s/9abbbe4/podcast/play/119871844/https%3A%2F%2Fd3ctxlq1ktw2nl.cloudfront.net%2Fstaging%2F2026-4-12%2Fbd8a7723-bb13-1a83-f585-f1d41f95e460.mp3 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/some-work-all-play-150821/episodes/310-the-fatigue-resistance-episode-rachel-entrekin-makes-history-at-cocodona-women-v-men-durability-fueling-and-the-central-nervous-system-brain-changes-and-more Duration seconds: 5642 ## Resource We had some HYPOTHESES for this amazing episode! The main topics all revolved around fatigue resistance (often called “durability” in the literature), which we think is the most exciting area of training theory and physiology. It started with Rachel Entrekin’s legendary overall win at the Cocodona 250, an event that explores some of the strangest and coolest parts of endurance. Our big theory: what we’re seeing in these wild ultras is directly connected to what we see in short distances. A new study looked at fatigue resistance variations between men and women, with some shocking results. We expand the scope to talk about the literature generally before going to some ideas for how it all might relate to the central nervous system. ...And how it relates to fueling. You could probably guess that we were going to talk about carbs. Plus, we answer questions about the culture of fueling for young athletes and feeling good after long runs! This one starts with a description of Megan’s health journey. The hottest vacation is apparently a 3-day stay in Boulder Community Hospital. Things are scary, but we’re holding onto hope for the future. We love you all! HUZZAH! -David and Megan Click "Get 40% Off" button for 40% off at The Feed here: thefeed.com/swap Buy Janji's amazing gear: https://janji.com (code "SWAP") The Wahoo KICKR Run is the best treadmill on the market: https://www.wahoofitness.com/devices/running/treadmills/kickr-run-buy (code “SWAP”) For training plans, weekly bonus podcasts, heart rate zones, articles, and videos: patreon.com/swap ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/some-work-all-play-150821/episodes/310-the-fatigue-resistance-episode-rachel-entrekin-makes-history-at-cocodona-women-v-men-durability-fueling-and-the-central-nervous-system-brain-changes-and-more/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/some-work-all-play-150821/310-the-fatigue-resistance-episode-rachel-entrekin-makes-history-at-cocodona-women-v-men-durability-fueling-and-the-central-nervous-system-brain-changes-and-more.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.