# Why Weight Loss Drugs Don't Work On Their Own Dr. Nick Fuller (480) Page: https://stenobird.com/podcast/shirtloads-of-science-720391/why-weight-loss-drugs-don-t-work-on-their-own-dr-nick-fuller-480 Text version: https://stenobird.com/podcast/shirtloads-of-science-720391/why-weight-loss-drugs-don-t-work-on-their-own-dr-nick-fuller-480.md Podcast: [Shirtloads of Science](https://stenobird.com/podcast/shirtloads-of-science-720391) Published: 2026-06-27T23:00:00+00:00 Episode link: https://shirtloadsofscience.libsyn.com/why-weight-loss-drugs-dont-last-without-lifestyle-change-with-dr-nick-fuller Audio file: https://traffic.libsyn.com/secure/shirtloadsofscience/SOS_480_NF_Weightloss_Drugs.mp3?dest-id=436327 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/shirtloads-of-science-720391/episodes/why-weight-loss-drugs-don-t-work-on-their-own-dr-nick-fuller-480 Duration seconds: 1447 ## Resource I'm joined by Dr Nick Fuller to dissect the long-term effectiveness of weight loss medications and why lasting results do actually require more than medication alone. Nick explains why evidence-based behavioural weight management programs remain the first-line approach to weight loss built on three key pillars: diet, exercise and sleep (did you even know that sleep plays a big role in regulating hunger hormones?!) Drawing on his team's research, Nick shares why many people regain weight after stopping medication and why behavioural change is essential for sustainable success (and keeping weight off for good!) ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/shirtloads-of-science-720391/episodes/why-weight-loss-drugs-don-t-work-on-their-own-dr-nick-fuller-480/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/shirtloads-of-science-720391/why-weight-loss-drugs-don-t-work-on-their-own-dr-nick-fuller-480.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.