# Episode 452: Why Natural Myelin Repair Stops Working for People with MS (And How It Could Be Re-Started!) with Dr. Larry Sherman

Page: https://stenobird.com/podcast/realtalk-ms-779631/episode-452-why-natural-myelin-repair-stops-working-for-people-with-ms-and-how-it-could-be-re-started-with-dr-larry-sherman
Text version: https://stenobird.com/podcast/realtalk-ms-779631/episode-452-why-natural-myelin-repair-stops-working-for-people-with-ms-and-how-it-could-be-re-started-with-dr-larry-sherman.md
Podcast: [RealTalk MS](https://stenobird.com/podcast/realtalk-ms-779631)
Published: 2026-04-29T16:10:00+00:00
Episode link: https://realtalkms.com/452
Audio file: https://traffic.libsyn.com/secure/realtalkms/Episode_452_Why_Natural_Myelin_Repair_Stops_Working_for_People_with_MS_with_Dr._Larry_Sherman.mp3?dest-id=570470
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Duration seconds: 1782

## Resource

Myelin repair is a natural function. But, for people living with MS, that ability to repair myelin eventually stops working. New research led by my guest, Dr. Larry Sherman, may explain why that happens and point to new possibilities for future myelin repair treatments. Dr. Sherman is a professor at the Oregon National Primate Research Center at Oregon Health & Science University, and his research focuses on how the brain and spinal cord respond to injury and disease, particularly in demyelinating conditions such as multiple sclerosis. We're also sharing some potentially good news for people living with non-relapsing secondary progressive MS in Europe, but not in the United States. We'll give you the details about an experimental drug that's just been submitted to the FDA and EMA for approval for treating relapsing forms of MS and primary progressive MS. We'll share the results of a study that focused on the impact of a cancer diagnosis on MS care. We'll tell you how Fernando Mendoza celebrated being named the #1 pick in this year's NFL draft. And we're sharing news about a new AI tool for your doctor. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Why myelin repair stops working for people living with MS :22 EMA's Committee for Medicinal Products for Human Use recommends approval of Tolebrutinib 1:35 Roche submits Fenebrutinib for FDA and EMA approval 4:45 Study results show the effect of a cancer diagnosis on MS care 6:13 The first pick in the 2026 NFL draft, Fernando Mendoza, partners with the National MS Society to launch the Mendoza Family Fund 9:43 OpenAI launches ChatGPT for Clinicians 10:56 Dr. Larry Sherman discusses why myelin repair stops working for people with MS, and how his team may have found a way to restart it 14:37 Share thi…

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