# Episode 198: Tirzepatide, using Beers, stent for carotid stenosis, and high dose flu vaccine

Page: https://stenobird.com/podcast/primary-care-update-1000928/episode-198-tirzepatide-using-beers-stent-for-carotid-stenosis-and-high-dose-flu-vaccine
Text version: https://stenobird.com/podcast/primary-care-update-1000928/episode-198-tirzepatide-using-beers-stent-for-carotid-stenosis-and-high-dose-flu-vaccine.md
Podcast: [Primary Care Update](https://stenobird.com/podcast/primary-care-update-1000928)
Published: 2026-01-22T19:50:20+00:00
Episode link: https://podcasters.spotify.com/pod/show/primary-care-update/episodes/Episode-198-Tirzepatide--using-Beers--stent-for-carotid-stenosis--and-high-dose-flu-vaccine-e3e1t1h
Audio file: https://anchor.fm/s/5693a5c/podcast/play/114405873/https%3A%2F%2Fd3ctxlq1ktw2nl.cloudfront.net%2Fstaging%2F2026-0-22%2F8b8c67b9-df27-b0f0-1050-8f9dfba326c6.mp3
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JSON: https://stenobird.com/v1/public/podcasts/primary-care-update-1000928/episodes/episode-198-tirzepatide-using-beers-stent-for-carotid-stenosis-and-high-dose-flu-vaccine
Duration seconds: 1644

## Resource

Join Mark, Kate, Henry and Gary as they discuss 4 new POEMs (Patient Oriented Evidence that Matters, studies with the potential to change practice): a summary of the evidence on tirzepatide (Zepbound) for weight loss, using the Beers list with your patients, high vs standard dose flu vaccine and the risk of hospitalization, and whether stent or endarterectomy are better than maximal medical therapy for patients with asymptomatic carotid stensosis. Here are the links: Essential Evidence Plus: www.essentialevidenceplus.com Tirzepatide systematic review: https://pubmed.ncbi.nlm.nih.gov/41015578/ Tirzepatide vs dulaglutide: https://pubmed.ncbi.nlm.nih.gov/41406444/ Applying the Beers list: https://pubmed.ncbi.nlm.nih.gov/40697073/ High vs standard dose flu vaccine: https://pubmed.ncbi.nlm.nih.gov/41115437/ Another high dose flu trial: https://pubmed.ncbi.nlm.nih.gov/39230284/ Asymptomatic carotid stenosis treatment: https://pubmed.ncbi.nlm.nih.gov/41269206/

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## Transcript

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