# Episode 192: anticoag duration, old drugs for insomnia, lower dose Ozempic, and aspirin + anticoag or anticoag alone

Page: https://stenobird.com/podcast/primary-care-update-1000928/episode-192-anticoag-duration-old-drugs-for-insomnia-lower-dose-ozempic-and-aspirin-anticoag-or-anticoag-alone
Text version: https://stenobird.com/podcast/primary-care-update-1000928/episode-192-anticoag-duration-old-drugs-for-insomnia-lower-dose-ozempic-and-aspirin-anticoag-or-anticoag-alone.md
Podcast: [Primary Care Update](https://stenobird.com/podcast/primary-care-update-1000928)
Published: 2025-10-29T20:04:44+00:00
Episode link: https://podcasters.spotify.com/pod/show/primary-care-update/episodes/Episode-192-anticoag-duration--old-drugs-for-insomnia--lower-dose-Ozempic--and-aspirin--anticoag-or-anticoag-alone-e3a7pq4
Audio file: https://anchor.fm/s/5693a5c/podcast/play/110404868/https%3A%2F%2Fd3ctxlq1ktw2nl.cloudfront.net%2Fstaging%2F2025-9-29%2Ff975d77b-717d-66e1-b750-ea70f4ec279f.mp3
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Duration seconds: 1795

## Resource

This week, Gary, Kate, Mark and Henry discuss the optimal duration of anticoagulation after a provoked DVT, using low doses of mirtazapine or amitriptyline in adults with insomnia, whether a lower dose of semaglutide is still effective for weight loss, and adding aspirin for patients with coronary heart disease, a stent and who are also on a DOAC for another indication. Links: NICE Barrett Esophagus guideline: https://pubmed.ncbi.nlm.nih.gov/38553042/ Essential Evidence Plus: www.essentialevidenceplus.com Duration of anticoagulation: https://pubmed.ncbi.nlm.nih.gov/40888734/ Mirtazapine or amitriptyline for insomnia: ttps://pubmed.ncbi.nlm.nih.gov/39814428/ Lower dose semaglutide for obesity: https://pubmed.ncbi.nlm.nih.gov/40934115/ Adding aspirin: N Engl J Med . 2025 Oct 23;393(16):1578-1588 https://pubmed.ncbi.nlm.nih.gov/40888725/

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