# Episode 187: incidental activity, a new definition of Alzheimers, blood test for CRC screening, and DORAs for sleep Page: https://stenobird.com/podcast/primary-care-update-1000928/episode-187-incidental-activity-a-new-definition-of-alzheimers-blood-test-for-crc-screening-and-doras-for-sleep Text version: https://stenobird.com/podcast/primary-care-update-1000928/episode-187-incidental-activity-a-new-definition-of-alzheimers-blood-test-for-crc-screening-and-doras-for-sleep.md Podcast: [Primary Care Update](https://stenobird.com/podcast/primary-care-update-1000928) Published: 2025-08-12T21:52:19+00:00 Episode link: https://podcasters.spotify.com/pod/show/primary-care-update/episodes/Episode-187-incidental-activity--a-new-definition-of-Alzheimers--blood-test-for-CRC-screening--and-DORAs-for-sleep-e36pg4s Audio file: https://anchor.fm/s/5693a5c/podcast/play/106790492/https%3A%2F%2Fd3ctxlq1ktw2nl.cloudfront.net%2Fstaging%2F2025-7-12%2Fd5335f3f-4bfe-2db1-76ad-9d5f3a667eb3.mp3 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/primary-care-update-1000928/episodes/episode-187-incidental-activity-a-new-definition-of-alzheimers-blood-test-for-crc-screening-and-doras-for-sleep Duration seconds: 2289 ## Resource This week, we found 4 great new studies for primary care physicians (and their patients): the health benefits of “incidental” activity, real world data and the amyloid cascade theory for Alzheimer’s disease, a new blood test for colorectal cancer screening, and DORAs for sleep. Check out Essential Evidence Plus: www.essentialevidenceplus.com Incidental activity: https://pubmed.ncbi.nlm.nih.gov/40228066/ New Alzheimer's definition in the real world: https://pubmed.ncbi.nlm.nih.gov/40359457/ Blood test for colorectal cancer screening: https://pubmed.ncbi.nlm.nih.gov/40455622/ "DORAs" for insomnia: https://pubmed.ncbi.nlm.nih.gov/40555730/ ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/primary-care-update-1000928/episodes/episode-187-incidental-activity-a-new-definition-of-alzheimers-blood-test-for-crc-screening-and-doras-for-sleep/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/primary-care-update-1000928/episode-187-incidental-activity-a-new-definition-of-alzheimers-blood-test-for-crc-screening-and-doras-for-sleep.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.