# Episode 185: resistant HTN tx, mirtazepine for sleep, baloxav for prevention, PRP for OA

Page: https://stenobird.com/podcast/primary-care-update-1000928/episode-185-resistant-htn-tx-mirtazepine-for-sleep-baloxav-for-prevention-prp-for-oa
Text version: https://stenobird.com/podcast/primary-care-update-1000928/episode-185-resistant-htn-tx-mirtazepine-for-sleep-baloxav-for-prevention-prp-for-oa.md
Podcast: [Primary Care Update](https://stenobird.com/podcast/primary-care-update-1000928)
Published: 2025-07-16T15:44:48+00:00
Episode link: https://podcasters.spotify.com/pod/show/primary-care-update/episodes/Episode-185-resistant-HTN-tx--mirtazepine-for-sleep--baloxav-for-prevention--PRP-for-OA-e35kome
Audio file: https://anchor.fm/s/5693a5c/podcast/play/105586830/https%3A%2F%2Fd3ctxlq1ktw2nl.cloudfront.net%2Fstaging%2F2025-6-16%2F51825b11-7835-9912-a834-0640cbcf8d9e.mp3
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JSON: https://stenobird.com/v1/public/podcasts/primary-care-update-1000928/episodes/episode-185-resistant-htn-tx-mirtazepine-for-sleep-baloxav-for-prevention-prp-for-oa
Duration seconds: 1979

## Resource

This week our intrepid primary care docs discuss 4 new POEMs: spironolactone vs amiloride for resistant hypertension, mirtazapine for insomnia in older adults, baloxivir for influenza post exposure prophylaxis, and platelet-rich plasma injections for knee osteoarthritis. We've got opinions! Show notes: Spironolactone vs amiloride for resistant hypertension: pubmed.ncbi.nlm.nih.gov/40366680/ Mirtazapine for chronic insomnia: https://pubmed.ncbi.nlm.nih.gov/40135470/ Baloxavir to prevent flu in household contacts: https://pubmed.ncbi.nlm.nih.gov/40267424/ Platelet-rich plasma for knee OA: https://pubmed.ncbi.nlm.nih.gov/39751394/

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## Transcript

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