# Designing Clinical Trials Balancing Simplicity with Complexity Page: https://stenobird.com/podcast/pharmatalkradio-7131046/designing-clinical-trials-balancing-simplicity-with-complexity Text version: https://stenobird.com/podcast/pharmatalkradio-7131046/designing-clinical-trials-balancing-simplicity-with-complexity.md Podcast: [PharmaTalkRadio](https://stenobird.com/podcast/pharmatalkradio-7131046) Published: 2026-01-27T15:56:48+00:00 Episode link: https://www.spreaker.com/episode/designing-clinical-trials-balancing-simplicity-with-complexity--69622422 Audio file: https://dts.podtrac.com/redirect.mp3/api.spreaker.com/download/episode/69622422/cmo_2025_balancing_simplicity_complexity_podcast.mp3 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/pharmatalkradio-7131046/episodes/designing-clinical-trials-balancing-simplicity-with-complexity Duration seconds: 1830 ## Resource When designing clinical trials, CMOs aim to answer meaningful questions for a plethora of stakeholders. Inherently, this results in study protocols with more measures, biomarkers and data collection that both provides a platform for strategic decision-making but also impacts patient burden, operational foot-print, timelines and cost. In this panel discussion from the 2025 Chief Medical Officer Summit 360°, CMOs address how to develop a balanced strategy that takes into account the ambition to answer these questions with the realities of complicated clinical trials. More specifically: Prioritizing data collection strategy to answer key scientific questions while avoiding overcomplication Designing trials around real patients rather than ideal patients Better understanding the objectives of the study and asking the questions that achieve those objectives Better partnering with patients and PIs To learn more about the Chief Medical Officer Summit 360°, please visit CMO360.org . ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/pharmatalkradio-7131046/episodes/designing-clinical-trials-balancing-simplicity-with-complexity/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/pharmatalkradio-7131046/designing-clinical-trials-balancing-simplicity-with-complexity.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.