# Balancing Innovation and Practicality in Immuno-Oncology Dose Selection

Page: https://stenobird.com/podcast/pharmatalkradio-7131046/balancing-innovation-and-practicality-in-immuno-oncology-dose-selection
Text version: https://stenobird.com/podcast/pharmatalkradio-7131046/balancing-innovation-and-practicality-in-immuno-oncology-dose-selection.md
Podcast: [PharmaTalkRadio](https://stenobird.com/podcast/pharmatalkradio-7131046)
Published: 2025-12-19T17:51:21+00:00
Episode link: https://www.spreaker.com/episode/balancing-innovation-and-practicality-in-immuno-oncology-dose-selection--69135639
Audio file: https://dts.podtrac.com/redirect.mp3/api.spreaker.com/download/episode/69135639/project_optimus.mp3
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JSON: https://stenobird.com/v1/public/podcasts/pharmatalkradio-7131046/episodes/balancing-innovation-and-practicality-in-immuno-oncology-dose-selection
Duration seconds: 2712

## Resource

About this podcast: Recorded at the 2025 IO360º Summit, this podcast addresses how Project Optimus is reshaping dose selection from maximum tolerated dose to a balance of efficacy and safety. More specifically, this panel addresses FDA objectives for multi-dose selection, alternative dose-selection strategies with imaging, biomarkers and tumor burden analysis, the higher costs and longer timelines, and financial impacts for early-phase oncology companies. For more information, go to IO360summit.com .

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## Transcript

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