# Bringing organ-scale cryopreservation into existence (Hunter Davis, Ep #6)

Page: https://stenobird.com/podcast/owl-posting-6974455/bringing-organ-scale-cryopreservation-into-existence-hunter-davis-ep-6
Text version: https://stenobird.com/podcast/owl-posting-6974455/bringing-organ-scale-cryopreservation-into-existence-hunter-davis-ep-6.md
Podcast: [Owl Posting](https://stenobird.com/podcast/owl-posting-6974455)
Published: 2025-11-24T14:56:44+00:00
Episode link: https://www.owlposting.com/p/bringing-organ-scale-cryopreservation
Audio file: https://api.substack.com/feed/podcast/179772630/02354fdbe6cd25035835572eeffca499.mp3
Processing state: not_requested
JSON: https://stenobird.com/v1/public/podcasts/owl-posting-6974455/episodes/bringing-organ-scale-cryopreservation-into-existence-hunter-davis-ep-6
Duration seconds: 6891

## Resource

Sponsor note: the supporter of this video is rush.cloud . If you are at all involved with doing preclinical drug discovery and would benefit from computational tools, you should check out their platform + beautiful website here: rush.cloud . If you’re at all interested in working together for future episodes, reach out! This is an interview with Hunter Davis , the CSO and co-founder (alongside Laura Deming ) of Until Labs , which you may also know by its prior name, Cradle. They are a biotech startup devoted to organ-scale cryopreservation. They raised a $58M Series A back in September 2025 , and are backed by Founders Fund (especially interesting!), Lux Ventures, and others. In this interview, we mainly talk about the engineering and scientific difficulties in the cryopreservation field, including some background details on their September 2024 progress report on neural slice rewarming , how they characterize tissue damage in their attempts to do kidney cryopreservation, the potential economics of future cryopreservation protocols, and lots more. One of the most interesting conversations I’ve had in a long time. If any of this work seems interesting , Until Labs is actively and aggressively hiring! Enjoy! Substack + Transcript: https://www.owlposting.com/p/bringing-organ-scale-cryopreservation Spotify: https://open.spotify.com/episode/23g2lR7dWl8NXUn893KMgv?si=5628cd0e56184130 Apple Podcasts: https://podcasts.apple.com/us/podcast/bringing-organ-scale-cryopreservation-into-existence/id1758545538?i=1000738128994 Youtube: https://youtu.be/xaqwPd3ujHg Timestamps: [00:01:50] Introduction [00:05:00] Why don’t we have reversible cryopreservation today? [00:07:05] Why is freezing necessary at all for preservation? [00:08:23] Let’s discuss cryoprotectant agents [00:14:09] Unti…

## Actions

- request_transcript: `POST https://stenobird.com/v1/public/podcasts/owl-posting-6974455/episodes/bringing-organ-scale-cryopreservation-into-existence-hunter-davis-ep-6/transcription-requests` — Idempotently request low-priority transcript generation for this episode.
- read_markdown: `GET https://stenobird.com/podcast/owl-posting-6974455/bringing-organ-scale-cryopreservation-into-existence-hunter-davis-ep-6.md` — Read the agent-friendly Markdown representation of this episode resource.

A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed.

## Transcript

Full transcripts are not published on public pages unless there is a clear rights basis.