# #180: 🎙️ She Reversed Her Biological Age with Katrin Dreissigacker

Page: https://stenobird.com/podcast/nina-s-notes-podcast-6700445/180-she-reversed-her-biological-age-with-katrin-dreissigacker
Text version: https://stenobird.com/podcast/nina-s-notes-podcast-6700445/180-she-reversed-her-biological-age-with-katrin-dreissigacker.md
Podcast: [Nina’s Notes Podcast](https://stenobird.com/podcast/nina-s-notes-podcast-6700445)
Published: 2026-05-06T08:00:00+00:00
Episode link: https://www.ninasnotes.xyz/p/180-interview-reversing-biological
Audio file: https://api.substack.com/feed/podcast/196573575/304c9e5975936fc90e54f9a2262b2150.mp3
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JSON: https://stenobird.com/v1/public/podcasts/nina-s-notes-podcast-6700445/episodes/180-she-reversed-her-biological-age-with-katrin-dreissigacker
Duration seconds: 3236

## Resource

In this episode, I sit down with Dr. Katrin Dreissigacker, a plastic surgeon turned longevity architect and founder of Epigenedit, to explore why hyperbaric oxygen therapy may be one of the most overlooked tools in longevity science. We talk about her journey from a small village in East Germany to becoming known as the “Queen of Needles,” how she reversed markers of biological aging, improved her VO2 max in midlife, and why oxygen, mitochondria, skin health, resilience, and reinvention are all deeply connected. Key Topics: * Hyperbaric oxygen therapy and its role in longevity * Innovations in aesthetic medicine and needling techniques * The impact of oxygen saturation on aging and skin health * Biomarkers of aging and how hyperbaric oxygen influences them * The use of peptides and biohacking for healthspan extension Timestamps: * 00:00 – Reversing Biological Age? The Power of Oxygen * 00:30 – From East Germany to Elite Medicine * 02:30 – Why She Chose Medicine (Unexpected Path) * 02:57 – What Is Aesthetic Medicine (Beyond Vanity) * 05:14 – “Queen of Needles” & Revolutionizing Fillers * 08:46 – First Encounter with Hyperbaric Oxygen Therapy * 11:24 – From Pandemic to Longevity Innovation * 12:43 – Why She Built Her Own HBOT Chamber * 16:22 – Can HBOT Really Improve VO2 Max? * 18:02 – How HBOT Actually Works (Simple Explanation) * 20:11 – Mild vs Medical HBOT: What’s the Difference? * 21:23 – What It Improves: Sleep, Recovery & Aging * 24:00 – How Often Should You Do HBOT? * 26:17 – Risks, Side Effects & Common Fears * 30:40 – The Real Benefits (Why You Don’t Feel It Immediately) * 33:29 – Skin, Collagen & The ‘Glow Effect’ * 36:04 – Who Should NOT Use HBOT? * 38:22 – Peptides: Hype or Breakthrough? * 42:48 – Biggest Misconceptions About HBOT * 44:24 – Most Overused Aes…

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