# Google’s Efforts to Build Patient-Facing AI: A Conversation with Drs. Alan Karthikesalingam and Anil Palepu

Page: https://stenobird.com/podcast/nejm-ai-grand-rounds-5875765/google-s-efforts-to-build-patient-facing-ai-a-conversation-with-drs-alan-karthikesalingam-and-anil-palepu
Text version: https://stenobird.com/podcast/nejm-ai-grand-rounds-5875765/google-s-efforts-to-build-patient-facing-ai-a-conversation-with-drs-alan-karthikesalingam-and-anil-palepu.md
Podcast: [NEJM AI Grand Rounds](https://stenobird.com/podcast/nejm-ai-grand-rounds-5875765)
Published: 2025-06-18T13:00:00+00:00
Episode link: https://ai-podcast.nejm.org/e/google-s-efforts-to-build-patient-facing-ai-a-conversation-with-drs-alan-karthikesalingam-and-anil-palepu/
Audio file: https://mcdn.podbean.com/mf/web/9g8czzhbvba4gjqy/Episode_31_Karthikesalingam_and_Palepu.mp3
Processing state: not_requested
JSON: https://stenobird.com/v1/public/podcasts/nejm-ai-grand-rounds-5875765/episodes/google-s-efforts-to-build-patient-facing-ai-a-conversation-with-drs-alan-karthikesalingam-and-anil-palepu
Duration seconds: 2302

## Resource

In this episode of NEJM AI Grand Rounds, guests Drs. Alan Karthikesalingam and Anil Palepu of Google walk co-hosts Raj Manrai and Andy Beam through the making and evaluation of AMIE, an AI system designed to conduct clinical conversations with patients. Alan and Anil explain how AMIE was trained using synthetic doctor-patient interactions generated by LLMs playing multiple roles—doctor, patient, critic, and moderator. They reveal how synthetic dialogue, guided by structured feedback and grounded in search, proved more effective than noisy real-world transcripts in building a model that could reason, ask questions, and show empathy. The discussion also covers what the “long tail” of medicine demands for building robust AI systems and how AMIE might one day augment real clinical workflows. Finally, Alan reflects on how AI has changed—and how it hasn’t—in the two years since he was last on the podcast. Transcript.

## Actions

- request_transcript: `POST https://stenobird.com/v1/public/podcasts/nejm-ai-grand-rounds-5875765/episodes/google-s-efforts-to-build-patient-facing-ai-a-conversation-with-drs-alan-karthikesalingam-and-anil-palepu/transcription-requests` — Idempotently request low-priority transcript generation for this episode.
- read_markdown: `GET https://stenobird.com/podcast/nejm-ai-grand-rounds-5875765/google-s-efforts-to-build-patient-facing-ai-a-conversation-with-drs-alan-karthikesalingam-and-anil-palepu.md` — Read the agent-friendly Markdown representation of this episode resource.

A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed.

## Transcript

Full transcripts are not published on public pages unless there is a clear rights basis.