# 180 | Limbic-Predominant Age-Related TDP-43 Encephalopathy (LATE) – A Conversation With Dr. David Wolk

Page: https://stenobird.com/podcast/navigating-neuropsychology-799474/180-limbic-predominant-age-related-tdp-43-encephalopathy-late-a-conversation-with-dr-david-wolk
Text version: https://stenobird.com/podcast/navigating-neuropsychology-799474/180-limbic-predominant-age-related-tdp-43-encephalopathy-late-a-conversation-with-dr-david-wolk.md
Podcast: [Navigating Neuropsychology](https://stenobird.com/podcast/navigating-neuropsychology-799474)
Published: 2025-12-01T08:30:00+00:00
Episode link: https://www.NavNeuro.com/180
Audio file: https://traffic.libsyn.com/secure/navneuro/NavNeuro_180_-_LATE_with_codewords.mp3?dest-id=768226
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JSON: https://stenobird.com/v1/public/podcasts/navigating-neuropsychology-799474/episodes/180-limbic-predominant-age-related-tdp-43-encephalopathy-late-a-conversation-with-dr-david-wolk
Duration seconds: 4854

## Resource

This episode is a conversation about the current state of knowledge with respect to the clinical-pathological entity of LATE. Topics covered include the relevant proteinopathy, pathologic overlap with FTLD and hippocampal sclerosis, the LATE clinical syndrome, similarities to and differences from Alzheimer's disease, the utility of clinical diagnostic criteria, neuroimaging markers, fluid biomarkers, clinical trials, and advice for identification and diagnosis of LATE. Show notes are available at www.NavNeuro.com/180 _________________ If you'd like to support the show, here are a few easy ways: 1) Get CE credits for listening to select episodes: www.NavNeuro.com/INS 2) Tell your friends and colleagues about it 3) Subscribe (free) and leave an Apple Podcasts rating/review: www.NavNeuro.com/itunes 4) Check out our book Becoming a Neuropsychologist , and leave it an Amazon rating Thanks for listening, and join us next time as we continue to navigate the brain and behavior! [Note: This podcast and all linked content is intended for general educational purposes only and does not constitute the practice of psychology or any other professional healthcare advice and services. No professional relationship is formed between hosts and listeners. All content is to be used at listeners' own risk. Users should always seek appropriate medical and psychological care from their licensed healthcare provider.]

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## Transcript

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