# TOFA: Boosting Fat Burn Without Appetite Suppression | Mesa News

Page: https://stenobird.com/podcast/mesa-news-today-2-min-news-the-daily-news-now-7559357/tofa-boosting-fat-burn-without-appetite-suppression-mesa-news
Text version: https://stenobird.com/podcast/mesa-news-today-2-min-news-the-daily-news-now-7559357/tofa-boosting-fat-burn-without-appetite-suppression-mesa-news.md
Podcast: [Mesa News Today | 2 Min News | The Daily News Now!](https://stenobird.com/podcast/mesa-news-today-2-min-news-the-daily-news-now-7559357)
Published: 2026-09-03T10:48:07+00:00
Episode link: https://sources.thednn.ai/1a411da9cb094b97
Audio file: https://api.fastcast.ai/audio/f675ee4e-2473-4059-8e1b-e8eb85c5c108.mp3
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Duration seconds: 100

## Resource

Scientists at UC Berkeley have discovered a new compound, TOFA, that fights obesity and metabolic diseases by boosting your body’s natural fat-burning power—not by suppressing appetite. In mice, TOFA increased energy expenditure by 18% without forcing behavioral changes, avoiding common side effects like nausea or muscle loss. Unlike popular GLP-1 drugs that curb hunger, TOFA targets metabolism directly, offering a fresh approach to weight management. Even more promising, combining TOFA with GLP-1s produced synergistic benefits in mice—improving weight, blood sugar, and fat levels. While still in early stages, the team has founded a company to begin human trials, bringing this potential game-changer closer to real-world use. Listen in comfort: Get a discount on a Soli Pillow: http://solipillow.com/discount/dnn. Advertise on DNN: advertise@thednn.ai This is an automated, high-level news summary based on public reporting. Report issues to feedback@thednn.ai. View sources & latest updates: https://sources.thednn.ai/1a411da9cb094b97

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## Transcript

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