# #448: Turning Sugar into Fiber, Hangover Science, and the Truth About Genetically Modified Probiotics | Zack Abbott Page: https://stenobird.com/podcast/longevity-with-nathalie-niddam-1367436/448-turning-sugar-into-fiber-hangover-science-and-the-truth-about-genetically-modified-probiotics-zack-abbott Text version: https://stenobird.com/podcast/longevity-with-nathalie-niddam-1367436/448-turning-sugar-into-fiber-hangover-science-and-the-truth-about-genetically-modified-probiotics-zack-abbott.md Podcast: [LONGEVITY with Nathalie Niddam](https://stenobird.com/podcast/longevity-with-nathalie-niddam-1367436) Published: 2026-06-19T09:00:00+00:00 Episode link: https://episode.flightcast.com/01KTRG2KTZE0GTT6DQE1ZW52XX.mp3 Audio file: https://episode.flightcast.com/01KTRG2KTZE0GTT6DQE1ZW52XX.mp3 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/longevity-with-nathalie-niddam-1367436/episodes/448-turning-sugar-into-fiber-hangover-science-and-the-truth-about-genetically-modified-probiotics-zack-abbott Duration seconds: 4605 ## Resource Today, I’m joined by Zack Abbott, a biotech innovator who took an unconventional path—from pharmaceutical science to the front lines of consumer health. Instead of following the well-worn route of drug development, Zack set his sights on bringing cutting-edge biotechnology directly to people, creating products designed not just for convenience, but for genuinely transforming our relationship with microbiology. Anyone who uses code NATNIDDAM will get 10% off their first order! Visit https://zbiotics.com/NATNIDDAM. Episode Timestamps: Podcast introduction and host background ... 00:00:00 Consumer impact versus traditional drug industry ... 00:06:06 Gap and opportunity for biotech in consumer space ... 00:06:42 Engineered probiotics: not hacks but new relationships with biology ... 00:07:19 Scientific and public responses to engineered probiotics ... 00:09:03 Technology behind genetically engineered probiotics explained ... 00:17:39 Bacillus subtilis: why it’s the ideal delivery vehicle ... 00:27:08 Sugar-to-fiber product mechanism and rationale ... 00:32:58 Importance of fiber quantity and diversity for gut health ... 00:42:26 Sugar-to-fiber: capabilities and limitations ... 00:54:06 Keto/carnivore implications and who benefits from sugar-to-fiber ... 00:57:51 Misunderstandings and realities about GMOs in consumer biotech ... 01:00:02 Regulation, safety, and honest claims in biotech supplements ... 01:07:01 Current science and future of the microbiome in longevity ... 01:12:14 Personalization, AI, and microbiome-directed health ... 01:13:10 Our Amazing Sponsors: MitoQ Hormonal Metabolic Control – A targeted formula designed to support women through the hormonal and metabolic shifts of perimenopause and menopause, featuring S-Equol for healthy estrogen signaling, B. breve… ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/longevity-with-nathalie-niddam-1367436/episodes/448-turning-sugar-into-fiber-hangover-science-and-the-truth-about-genetically-modified-probiotics-zack-abbott/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/longevity-with-nathalie-niddam-1367436/448-turning-sugar-into-fiber-hangover-science-and-the-truth-about-genetically-modified-probiotics-zack-abbott.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.