# #428: Poop, Peptides & The Power of Microbiome | The Secret Longevity Organ With Dr. Grace Liu

Page: https://stenobird.com/podcast/longevity-with-nathalie-niddam-1367436/428-poop-peptides-the-power-of-microbiome-the-secret-longevity-organ-with-dr-grace-liu
Text version: https://stenobird.com/podcast/longevity-with-nathalie-niddam-1367436/428-poop-peptides-the-power-of-microbiome-the-secret-longevity-organ-with-dr-grace-liu.md
Podcast: [LONGEVITY with Nathalie Niddam](https://stenobird.com/podcast/longevity-with-nathalie-niddam-1367436)
Published: 2026-04-10T09:00:00+00:00
Episode link: https://episode.flightcast.com/01KNNK15SW5J8127BVG2SSH55H.mp3
Audio file: https://episode.flightcast.com/01KNNK15SW5J8127BVG2SSH55H.mp3
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JSON: https://stenobird.com/v1/public/podcasts/longevity-with-nathalie-niddam-1367436/episodes/428-poop-peptides-the-power-of-microbiome-the-secret-longevity-organ-with-dr-grace-liu
Duration seconds: 5097

## Resource

Today, I'm joined by Dr. Grace Liu, often known as the “Gut Goddess,” a trailblazer in the world of microbiome science and founder of The Gut Institute. In this conversation, we take a bold dive into an often-overlooked pillar of longevity: your poop. That's right—Dr. Liu unpacks the fascinating and sometimes surprising science showing how gut health shapes everything from your immune system and brain to your lifespan itself. Episode Timestamps: Introduction to host ... 00:00:00 Dr. Grace Liu on the gut as a hallmark of aging ... 00:04:06 Peptides, FMT, and evidence for gut-driven regeneration ... 00:05:04 FMT safety, immune education, and the environmental “microdosing” effect ... 00:07:07 Links between gut aging, the immune system, and mental health ... 00:08:13 Diet, ancestry, and resistant starch for butyrate production ... 00:15:01 Ancestral diet, microbiome differences, and pitfalls of shortcuts ... 00:18:53 Fiber, polyphenols, and the key longevity bacteria ... 00:24:09 Gut markers, loss of diversity, and ABC species signature ... 00:25:15 Risks of overhyped probiotics, strep, and broad interventions ... 00:36:29 Peptides, bioregulators, and repairing the gut ... 01:12:01 Practical longevity: movement, daily habits & where to learn more ... 01:22:46 Our Amazing Sponsors: Tro Zzz by Troscriptions – A fast-acting sleep troche that dissolves in your cheek and combines melatonin with compounds like honokiol, adenosine, cordycepin, CBD, CBN, and 5-HTP to support deep, restorative sleep when travel, stress, or late workouts throw things off. Head to troscriptions.com and use code NAT10 for 10% off your first order. O₃RACLE by Wizard Sciences — A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without cl…

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