# 144: What Is Insulin Resistance? The Hidden Driver of Weight Gain, Fatigue, and Inflammation | Lizzie Ens

Page: https://stenobird.com/podcast/lizzie-ens-show-7085348/144-what-is-insulin-resistance-the-hidden-driver-of-weight-gain-fatigue-and-inflammation-lizzie-ens
Text version: https://stenobird.com/podcast/lizzie-ens-show-7085348/144-what-is-insulin-resistance-the-hidden-driver-of-weight-gain-fatigue-and-inflammation-lizzie-ens.md
Podcast: [Lizzie Ens Show](https://stenobird.com/podcast/lizzie-ens-show-7085348)
Published: 2026-06-09T08:00:00+00:00
Episode link: https://lizzie-ens-show.captivate.fm
Audio file: https://episodes.captivate.fm/episode/9a6c536f-1301-4b36-9910-5503cd9e5b88.mp3
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Duration seconds: 1784

## Resource

What if the reason you cannot lose weight, you are always tired, and your labs keep coming back "normal" is a condition affecting up to 40% of adults that most doctors are not even testing for? In this solo episode, Lizzie breaks down everything you need to know about insulin resistance: what it is, why it is quietly behind so much of the weight gain, fatigue, inflammation, and metabolic chaos she sees in her clients every day, and most importantly, what you can actually do about it without going straight for medication. She shares the specific lab test your doctor is likely skipping, walks through a real client story that shows exactly how this plays out, shares her own personal experience going into insulin resistance from chronic stress and poor sleep, and lays out the research-backed lifestyle changes that have been shown to rival medication for blood sugar and insulin management. This is the episode for anyone who has been doing everything right and still cannot figure out why their body is not responding. The answer might be in a number your doctor has never checked. In this episode, you’ll learn: Why up to 40% of adults have insulin resistance and most have no idea, including what is quietly happening in your body before any obvious symptoms show up The single most important lab test for metabolic health that is missing from most standard blood panels and exactly what to ask your doctor for How visceral fat, PCOS, fatty liver disease, cardiovascular disease, and cognitive decline are all downstream effects of unmanaged insulin resistance Why stress and poor sleep can drive you into insulin resistance even when your diet is completely clean, and how Lizzie experienced this firsthand The role of muscle mass in glucose disposal and why strength training is one of t…

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## Transcript

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