# Low-Grade Serous Ovarian Cancer — Rapid Case Review: Microlearning Activity 2

Page: https://stenobird.com/podcast/gynecologic-oncology-update-612940/low-grade-serous-ovarian-cancer-rapid-case-review-microlearning-activity-2
Text version: https://stenobird.com/podcast/gynecologic-oncology-update-612940/low-grade-serous-ovarian-cancer-rapid-case-review-microlearning-activity-2.md
Podcast: [Gynecologic Oncology Update](https://stenobird.com/podcast/gynecologic-oncology-update-612940)
Published: 2026-09-14T16:00:00+00:00
Episode link: https://gynecologic-oncology.captivate.fm/episode/6128-lgso2026-2-rapidcasereview
Audio file: https://dts.podtrac.com/redirect.mp3/episodes.captivate.fm/episode/4e030fa4-91a4-4b2b-b26c-563fb3bfc43d.mp3
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JSON: https://stenobird.com/v1/public/podcasts/gynecologic-oncology-update-612940/episodes/low-grade-serous-ovarian-cancer-rapid-case-review-microlearning-activity-2
Duration seconds: 1581

## Resource

Featuring perspectives from Dr Rachel N Grisham, including the following topics: Case: A woman in her early 40s with recurrent low-grade serous ovarian cancer (LGSOC) and prior treatment with a MEK inhibitor receives avutometinib/defactinib on the RAMP 301 trial (0:00) Case: A woman in her early 70s with recurrent KRAS-mutated LGSOC receives avutometinib/defactinib and develops muscle weakness (10:03) Case: A woman in her late 70s with KRAS-mutated recurrent LGSOC develops congestive heart failure on trametinib and then receives avutometinib/defactinib (16:15) Case: A woman in her mid 60s with recurrent BRAF V600E LGSOC has concerns about side effects and receives single-agent dabrafenib (19:49) CME information and select publications

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## Transcript

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