# Low-Grade Serous Ovarian Cancer — 5-Minute Journal Club: Microlearning Activity 1

Page: https://stenobird.com/podcast/gynecologic-oncology-update-612940/low-grade-serous-ovarian-cancer-5-minute-journal-club-microlearning-activity-1
Text version: https://stenobird.com/podcast/gynecologic-oncology-update-612940/low-grade-serous-ovarian-cancer-5-minute-journal-club-microlearning-activity-1.md
Podcast: [Gynecologic Oncology Update](https://stenobird.com/podcast/gynecologic-oncology-update-612940)
Published: 2026-09-13T13:00:00+00:00
Episode link: https://gynecologic-oncology.captivate.fm/episode/6124-lgso2026-1-5mjc
Audio file: https://dts.podtrac.com/redirect.mp3/episodes.captivate.fm/episode/df3f5dad-a1fa-40d4-9c41-daaaefca986d.mp3
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JSON: https://stenobird.com/v1/public/podcasts/gynecologic-oncology-update-612940/episodes/low-grade-serous-ovarian-cancer-5-minute-journal-club-microlearning-activity-1
Duration seconds: 1726

## Resource

Featuring perspectives from Dr Rachel N Grisham, including the following topics: Mechanism, clinical evidence and practical use of avutometinib with defactinib for recurrent low-grade serous ovarian cancer (LGSOC) (0:00) A Phase III trial of letrozole alone as front-line treatment for LGSOC (11:11) Current and future role of avutometinib with defactinib for LGSOC (19:23) A Phase II/III trial of trametinib for recurrent LGSOC: Biomarker analyses and clinical implications (21:37) CME information and select publications

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## Transcript

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