# 272 Slowing Biological Aging Naturally: Autophagy, Diet and Longevity with Leslie Kenny

Page: https://stenobird.com/podcast/growing-older-living-younger-about-longevity-wellness-healthspan-3700595/272-slowing-biological-aging-naturally-autophagy-diet-and-longevity-with-leslie-kenny
Text version: https://stenobird.com/podcast/growing-older-living-younger-about-longevity-wellness-healthspan-3700595/272-slowing-biological-aging-naturally-autophagy-diet-and-longevity-with-leslie-kenny.md
Podcast: [Growing Older Living Younger: About longevity, wellness, healthspan,](https://stenobird.com/podcast/growing-older-living-younger-about-longevity-wellness-healthspan-3700595)
Published: 2026-06-15T09:00:00+00:00
Episode link: https://golyproject.libsyn.com/272-slowing-biological-aging-naturally-autophagy-diet-and-longevity-with-leslie-kenny
Audio file: https://dts.podtrac.com/redirect.mp3/traffic.libsyn.com/secure/golyproject/kenny.mp3?dest-id=2765309
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JSON: https://stenobird.com/v1/public/podcasts/growing-older-living-younger-about-longevity-wellness-healthspan-3700595/episodes/272-slowing-biological-aging-naturally-autophagy-diet-and-longevity-with-leslie-kenny
Duration seconds: 2670

## Resource

What if one of the most powerful anti-aging tools already exists within your body? This episode explores autophagy, the body's natural cellular renewal system, and how activating it can support healthy aging and longevity. Longevity expert Leslie Kenny shares her personal journey of reversing autoimmune disease and translating cutting-edge science into practical strategies. Listeners will discover how autophagy promoting spermidine, proper nutrition, and baseline lifestyle habits influence cellular repair, resilience, and biological aging. L eslie Kenny is the founder of Oxford Healthspan , a company focused on translating longevity science into practical health solutions. She is a longevity researcher with expertise in cellular aging, autophagy, and immune system modulation. Her career includes work in finance and policy before a personal medical crisis led her to transition into health science. She specializes in spermidine research and its role in activating autophagy and influencing the hallmarks of aging. She is co-founder of the Oxford Longevity Project, a nonprofit dedicated to education in healthy aging. Episode Timeline 00:00 – Welcome and introduction 02:00 – Reframing aging as a modifiable biological process 03:50 – Leslie Kenny's autoimmune diagnosis and turning point 10:50 – Limitations of modern healthcare and the need for prevention 14:50 – What autophagy is and why it matters for longevity 17:00 – Spermidine and its role in cellular renewal pathways 21:30 – Nutrition, mushrooms, and dietary sources of spermidine 24:30 – Hallmarks of aging and systemic cellular decline 31:00 – Development of Primadine and supplement formulation science 37:00 – Practical strategies: fasting, diet, and supplementation 41:30 – Key takeaways on influencing biological agin Co…

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