# 54. Immunotherapy Breakthroughs with Dr. Gregory Friedman

Page: https://stenobird.com/podcast/game-over-c-ncer-6947500/54-immunotherapy-breakthroughs-with-dr-gregory-friedman
Text version: https://stenobird.com/podcast/game-over-c-ncer-6947500/54-immunotherapy-breakthroughs-with-dr-gregory-friedman.md
Podcast: [Game Over: c*ncer](https://stenobird.com/podcast/game-over-c-ncer-6947500)
Published: 2026-07-07T13:00:02+00:00
Episode link: https://www.spreaker.com/episode/54-immunotherapy-breakthroughs-with-dr-gregory-friedman--72839876
Audio file: https://api.spreaker.com/download/episode/72839876/ep54_dr_gregory_friedman.mp3
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JSON: https://stenobird.com/v1/public/podcasts/game-over-c-ncer-6947500/episodes/54-immunotherapy-breakthroughs-with-dr-gregory-friedman
Duration seconds: 2163

## Resource

What does the future of pediatric cancer treatment actually look like? In this episode of Game Over: c*ncer, hosts Dana Nichols and Val Solomon sit down with Dr. Gregory Friedman pediatric oncologist, CKc-funded researcher, and chair of the Scientific Advisory Board at Cannonball Kids’ cancer Foundation (CKc), to talk about one of the most exciting areas in childhood cancer research: oncolytic viral therapy. Dr. Friedman explains how modified cold sore viruses can be used to safely target and kill pediatric brain tumor cells while also triggering the child’s immune system to attack the tumor. He shares the science behind this innovative immunotherapy approach, what his clinical trials have shown so far, and why the future of pediatric brain tumor treatment may depend on combination therapies that work with the immune system rather than against it. If you’re interested in pediatric cancer research, immunotherapy, brain tumor treatment, clinical trials, childhood cancer advocacy, or how nonprofit funding helps move science forward, this episode is packed with insight. In this episode, we cover: What oncolytic viral therapy is and how it works in pediatric brain tumors Why traditional immunotherapy has struggled in childhood brain cancers How modified viruses may help the immune system recognize and attack cancer Early clinical trial outcomes in children with high-grade glioma Why pediatric cancers need pediatric-specific treatments How research moves from the lab to clinical trials The role of the Scientific Advisory Board at CKc Why funding pediatric cancer clinical trials is so important What the future of immunotherapy for childhood cancer may look like over the next decade Dr. Friedman also shares why he believes we may be approaching a new era in pediatric cancer tr…

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