# Can Aging Be Reversed by Science?

Page: https://stenobird.com/podcast/foodnourish-deep-dives-7306766/can-aging-be-reversed-by-science
Text version: https://stenobird.com/podcast/foodnourish-deep-dives-7306766/can-aging-be-reversed-by-science.md
Podcast: [Foodnourish Deep Dives](https://stenobird.com/podcast/foodnourish-deep-dives-7306766)
Published: 2026-05-19T17:35:03+00:00
Episode link: https://www.spreaker.com/episode/can-aging-be-reversed-by-science--71677202
Audio file: https://dts.podtrac.com/redirect.mp3/api.spreaker.com/download/episode/71677202/programming_cells_to_reverse_aging.mp3
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JSON: https://stenobird.com/v1/public/podcasts/foodnourish-deep-dives-7306766/episodes/can-aging-be-reversed-by-science
Duration seconds: 1349

## Resource

Can aging be reversed, or slowed in a meaningful way. This episode covers cellular reprogramming, OSK, Yamanaka factors, epigenetic aging, and the key studies behind the claims. You will hear what the mouse data showed, what chemical reprogramming achieved in human cells, and where the science still has limits. References: Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors The original 2006 iPS paper. It introduced the four factors Oct3/4, Sox2, c-Myc, and Klf4. Source Reprogramming to recover youthful epigenetic information and restore vision This Nature paper reported that OSK restored youthful DNA methylation patterns, promoted axon regeneration, and reversed vision loss in mouse models. Source Full text via PubMed Central for the OSK vision paper Useful if you want the full paper without a paywall. Source Chemically induced reprogramming to reverse cellular aging This paper reported six chemical cocktails that restored a youthful transcript profile in human cells in under a week, without changing cell identity. Source Full text for the chemical reprogramming paper Direct publisher link to the full study. Source Loss of epigenetic information as a cause of mammalian aging The Cell paper that lays out the epigenetic information loss model of aging. Source ClinicalTrials.gov listing, NCT07290244 A ClinicalTrials.gov study page connected to this area of research. Source Support our work. Make a small donation. This removes any advertisements and help us continue bringing more interesting topics and confronting mainstream narrative on health. Click the Link to support us: https://www.spreaker.com/podcast/foodnourish-deep-dives--6602003/support 🤗 Support the show: Become a supporter for just 2€ per month to remove ad…

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## Transcript

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