Episode
Diving Into Low Dose Naltrexone
- Podcast
- FIAT Health Podcast
- Published
- Nov 19, 2025
- Duration seconds
- 1521
- Processing state
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Summary
In this episode of the Fiat Health Podcast, Caroline and Maddie discuss Low Dose Naltrexone (LDN)—a medication originally for addiction that is now used for autoimmune, inflammatory, mental health, pain, and fertility conditions. They dive into the science behind how LDN modulates the immune system and how a low dose of this medication affects the body differently than high doses. Caroline and Maddie also share the benefits, possible side effects, and why they believe LDN can be part of a holistic approach to women's health. Medical Disclaimer: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment. Key Takeaways: Low Dose Naltrexone (LDN) - Naltrexone is a medication originally developed for addiction treatment at high doses, but at low doses (usually below 4.5mg), it acts differently in the body—modulating the immune system, reducing inflammation, and increasing endorphin production without suppressing immunity. LDN Uses - LDN is being increasingly used for a wide variety of conditions, particularly autoimmune and inflammatory disorders (such as Hashimoto's, rheumatoid arthritis, lupus, psoriasis, Crohn's, ulcerative colitis), chronic pain (fibromyalgia, migraines), and women's health and fertility issues (PMS, endometriosis, PCOS, painful periods), as well as some mood and neurological conditions. Side Effects - LDN is generally well tolerated, but common side effects can include sleep disturbances (difficulty sleeping, vivid dreams), mild GI upset, or headaches. Dosing is ramped up gradually and can be tailored based on individual respons…