# Your Best Shot: Holistic Approach to GLP-1

Page: https://stenobird.com/podcast/evolution-of-medicine-podcast-391904/your-best-shot-holistic-approach-to-glp-1
Text version: https://stenobird.com/podcast/evolution-of-medicine-podcast-391904/your-best-shot-holistic-approach-to-glp-1.md
Podcast: [Evolution of Medicine Podcast](https://stenobird.com/podcast/evolution-of-medicine-podcast-391904)
Published: 2026-02-23T16:14:00+00:00
Episode link: https://goevomed.libsyn.com/your-best-shot-holistic-approach-to-glp-1
Audio file: https://traffic.libsyn.com/secure/goevomed/EOM_EP_17.mp3?dest-id=234756
Processing state: not_requested
JSON: https://stenobird.com/v1/public/podcasts/evolution-of-medicine-podcast-391904/episodes/your-best-shot-holistic-approach-to-glp-1
Duration seconds: 2172

## Resource

In this episode of The Evolution of Medicine, host James Maskell interviews registered dietitian Ashley Koff about her new book Your Best Shot. The conversation explores the seismic impact of GLP-1 agonists like Ozempic and Wegovy—and how functional medicine can pivot from a "weight loss" mindset to a "weight health" approach. Koff reframes these medications not as magic bullets, but as biosimilar hormone replacement tools that "switch on" receptor sites—without repairing the underlying ecosystem. She outlines a five-part Weight Health Hormone assessment and introduces a Physician–Dietitian–Health Coach triad to ensure sustainable outcomes. The episode challenges practitioners to stay "agnostic about the agonist" and instead focus on metabolic repair, patient education, and structured team-based care. About the Guest: Ashley Koff, RD is a registered dietitian and functional nutrition expert focused on metabolic health, personalized nutrition, and hormone signaling. She is the author of Your Best Shot and advocates for a "Weight Health" approach that integrates assessment, repair, and team-based implementation. Ashley Koff, RD Website: https://thebetternutritionprogram.com/your-best-shot/#Order?utm_source=ig&utm_medium=social&utm_content=link_in_bio&fbclid=PAZXh0bgNhZW0CMTEAc3J0YwZhcHBfaWQMMjU2MjgxMDQwNTU4AAGn0Q9_BL_AVS4TE9ropSLtTkwP2y5sIOqKsbxZaaKPv3nNMm0Tq8QuWidcGUk_aem_U9Z5knW9eqsiMjw19fzflA Instagram: https://www.instagram.com/ashleykoffapproved/?hl=en Facebook: https://www.facebook.com/ashleykoffapproved/ Linkedin: https://www.linkedin.com/in/ashley-koff/ James Maskell Website: https://www.jamesmaskell.com/ Instagram: https://www.instagram.com/mrjamesmaskell Facebook: https://www.facebook.com/jamesedwardmaskell/ LinkedIn: https://www.linkedin.com/in/jam…

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