# Ep. 643 What Menopause Does to Lp(a) and Cholesterol |Menopause, Perimenopause, Cholesterol Page: https://stenobird.com/podcast/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/ep-643-what-menopause-does-to-lp-a-and-cholesterol-menopause-perimenopause-cholesterol Text version: https://stenobird.com/podcast/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/ep-643-what-menopause-does-to-lp-a-and-cholesterol-menopause-perimenopause-cholesterol.md Podcast: [Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+](https://stenobird.com/podcast/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097) Published: 2026-09-17T07:00:00+00:00 Episode link: https://traffic.megaphone.fm/CTH6150518637.mp3 Audio file: https://traffic.megaphone.fm/CTH6150518637.mp3 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/episodes/ep-643-what-menopause-does-to-lp-a-and-cholesterol-menopause-perimenopause-cholesterol Duration seconds: 2472 ## Resource Welcome to the latest Midlife Minute. This episode unpacks ongoing research on Lp(a), explores how women’s lipids change during the perimenopause-to-menopause transition, and clarifies what we can do about it. Stay tuned for more! IN THIS EPISODE, YOU WILL LEARN: How total cholesterol, LDL, and ApoB tend to rise most steeply around the final menstrual period, rather than increasing gradually with chronological aging Why women should have their Lp(a) checked both before and after menopause How oral and transdermal estradiol can affect LDL, HDL, triglycerides, and Lp(a) differently Why I recommend including ApoB when checking your lipids during the perimenopause window How your lifestyle can reduce your cardiovascular risk, even when your Lp(a) is elevated Why omega-3 fatty acids and commonly used lipid medications do not lower Lp(a) Why supplements are not replacements for statins in genuinely high-risk patients  I review the various PCSK9 inhibitors currently available, how they are administered, and their effects  How a CAC, a CT angiogram, and an AI-assisted CT angiogram can help women and their providers determine how aggressive their approach should be when Lp(a) is elevated Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website. Submit your questions to support@cynthiathurlow.com  Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.  Purchase Cynthia’s book, The Menopause Gut. Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement Line References: 1. Menopause Transition and Cardiovascular Disease Risk: Implications for Timing of Early Prevention: A Scientific Statement From the American Heart Association.Circulation. 2020.… ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/episodes/ep-643-what-menopause-does-to-lp-a-and-cholesterol-menopause-perimenopause-cholesterol/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/ep-643-what-menopause-does-to-lp-a-and-cholesterol-menopause-perimenopause-cholesterol.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.