# Ep. 629 The Gut's Role in Hormones, Metabolism, and Immunity | Menopause, Perimenopause, Gut Health Page: https://stenobird.com/podcast/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/ep-629-the-gut-s-role-in-hormones-metabolism-and-immunity-menopause-perimenopause-gut-health Text version: https://stenobird.com/podcast/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/ep-629-the-gut-s-role-in-hormones-metabolism-and-immunity-menopause-perimenopause-gut-health.md Podcast: [Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+](https://stenobird.com/podcast/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097) Published: 2026-08-13T07:00:00+00:00 Episode link: https://traffic.megaphone.fm/CTH6024788525.mp3 Audio file: https://traffic.megaphone.fm/CTH6024788525.mp3 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/episodes/ep-629-the-gut-s-role-in-hormones-metabolism-and-immunity-menopause-perimenopause-gut-health Duration seconds: 882 ## Resource Welcome to the latest summer version of the Midlife Minute.  In this episode, we’re focusing on the gut. Even though I’ve written a book about the gut microbiome changes that occur in perimenopause and menopause, I’m often asked whether the gut is truly central to midlife. So today, I provide direct answers to the many questions I received on this topic.   IN THIS EPISODE, YOU WILL LEARN: How the gut microbiome and estrogen work together, and the importance of supporting both  How the estrobolome helps recycle estrogen, and why its function could decline during menopause How poor sleep, blood sugar instability, histamine issues, and dysbiosis tend to be interconnected The value of practitioner-guided microbiome testing when investigating histamine intolerance, dysbiosis, and weight loss resistance Various factors that could contribute to weight loss resistance How my approach to stool testing has evolved as newer microbiome testing technology has become available Essential lifestyle habits for supporting gut health Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website. Submit your questions to support@cynthiathurlow.com  Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.  Purchase Cynthia’s book, The Menopause Gut. Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement Line ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/episodes/ep-629-the-gut-s-role-in-hormones-metabolism-and-immunity-menopause-perimenopause-gut-health/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/ep-629-the-gut-s-role-in-hormones-metabolism-and-immunity-menopause-perimenopause-gut-health.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.