# Ep. 605 "What Happens When You Stop the Pill in Midlife?" | Oral Contraceptives, Menopause, Perimenopause, Hormones Page: https://stenobird.com/podcast/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/ep-605-what-happens-when-you-stop-the-pill-in-midlife-oral-contraceptives-menopause-perimenopause-hormones Text version: https://stenobird.com/podcast/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/ep-605-what-happens-when-you-stop-the-pill-in-midlife-oral-contraceptives-menopause-perimenopause-hormones.md Podcast: [Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+](https://stenobird.com/podcast/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097) Published: 2026-06-11T07:00:00+00:00 Episode link: https://traffic.megaphone.fm/CTH1864432822.mp3 Audio file: https://traffic.megaphone.fm/CTH1864432822.mp3 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/episodes/ep-605-what-happens-when-you-stop-the-pill-in-midlife-oral-contraceptives-menopause-perimenopause-hormones Duration seconds: 2272 ## Resource Welcome to the latest Midlife Minute. Today, I’m taking a closer look at oral contraceptive use in perimenopause and menopause, exploring how oral contraceptives work, how they suppress or blunt perimenopausal and menopausal symptoms, alter hormone signaling and testing, what women may experience when they stop taking them, and why the gut microbiome is an essential part of the conversation. IN THIS EPISODE, YOU WILL LEARN: How oral contraceptives suppress certain key signaling hormones, making it difficult to assess women’s menopausal status accurately What women may experience when transitioning off oral contraceptives How long-term oral contraceptive use can alter gut microbial function and inflammatory pathways The association between long-term oral contraceptive use and nutrient depletion Why the standard reproductive hormone markers used to assess menopause (especially FSH/LH) are unreliable while on the pill How the microbiome changes that occur as women age may compound the effects of previous oral contraceptive use Helpful dietary, microbiome, and lifestyle strategies to support women navigating the post-pill transition Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia’s website. Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia’s book, The Menopause Gut. Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Resources: Sitruk-Ware R, Nath A. Characteristics and metabolic effects of estrogen and progestins contained in oral contraceptive pills. Best Practice and Research: Clinical Endocrinology and Metabolism. 2013;27(1):13–24. doi:10.1016/j.beem.2012.09.004 Schaffir J, Worly BL, G… ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/episodes/ep-605-what-happens-when-you-stop-the-pill-in-midlife-oral-contraceptives-menopause-perimenopause-hormones/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/ep-605-what-happens-when-you-stop-the-pill-in-midlife-oral-contraceptives-menopause-perimenopause-hormones.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.