# Ep. 602 “The Gallbladder-Hormone Connection” – How Perimenopause Changes Bile Flow and Gallbladder Health | Menopause, Perimenopause, Gallbladder Health

Page: https://stenobird.com/podcast/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/ep-602-the-gallbladder-hormone-connection-how-perimenopause-changes-bile-flow-and-gallbladder-health-menopause-perimenopause-gallbladder-health
Text version: https://stenobird.com/podcast/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/ep-602-the-gallbladder-hormone-connection-how-perimenopause-changes-bile-flow-and-gallbladder-health-menopause-perimenopause-gallbladder-health.md
Podcast: [Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+](https://stenobird.com/podcast/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097)
Published: 2026-06-04T07:00:00+00:00
Episode link: https://traffic.megaphone.fm/CTH7584028229.mp3
Audio file: https://traffic.megaphone.fm/CTH7584028229.mp3
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Duration seconds: 2023

## Resource

Welcome to this week’s Midlife Minute. Today, I’m focusing on all the questions I received about gallbladder health, including HRT-provoking symptoms, supplements that improve gallbladder health, and evidence-based food interventions. IN THIS EPISODE, YOU WILL LEARN: Why the risk of gallstones and gallbladder inflammation increases during the menopause transition How estrogen and progesterone HRT have different effects on gallbladder functioning The differences in risk between transdermal and oral HRT How the progesterone in HRT can cause gallbladder issues in some women What TUDCA is, and how it supports gallbladder health The value of TUDCA for women who have had their gallbladders removed How various nutrients and supplements support bile flow and gallbladder health What can contribute to gallstone formation Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia’s website. Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia’s book, The Menopause Gut. Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Gallbladder Research: Cabrera D, Arab JP, Arrese M. UDCA, NorUDCA, and TUDCA in liver diseases: a review of their mechanisms of action and clinical applications. Seminars in Liver Disease. 2019;39(4):397–404. doi:10.1055/s-0039-1696799 Vang S, Longley K, Steer CJ, Low WC. The unexpected uses of urso- and tauroursodeoxycholic acid in the treatment of non-liver diseases. Global Advances in Health and Medicine. 2014;3(3):58–69. doi:10.7453/gahmj.2014.017 Bai M, Yang L, Liao H, et al. Tauroursodeoxycholic acid improves nonalcoholic fatty liver disease by regulating gut microbiota and bile acid meta…

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