# Pulsed Field Ablation, Atrial Fibrillation Progression & Leadless Pacing | EP Edge Journal Watch – Jan 2026 (Issue 5)

Page: https://stenobird.com/podcast/ep-edge-journal-watch-7561379/pulsed-field-ablation-atrial-fibrillation-progression-leadless-pacing-ep-edge-journal-watch-jan-2026-issue-5
Text version: https://stenobird.com/podcast/ep-edge-journal-watch-7561379/pulsed-field-ablation-atrial-fibrillation-progression-leadless-pacing-ep-edge-journal-watch-jan-2026-issue-5.md
Podcast: [EP Edge Journal Watch](https://stenobird.com/podcast/ep-edge-journal-watch-7561379)
Published: 2026-01-05T10:30:00+00:00
Episode link: https://share.transistor.fm/s/2f092ade
Audio file: https://media.transistor.fm/2f092ade/6468fd63.mp3
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JSON: https://stenobird.com/v1/public/podcasts/ep-edge-journal-watch-7561379/episodes/pulsed-field-ablation-atrial-fibrillation-progression-leadless-pacing-ep-edge-journal-watch-jan-2026-issue-5
Duration seconds: 2033

## Resource

EP Edge Journal Watch — January 2026 | Issue #5 Pulsed Field Ablation, Device Therapy, and the Era of Personalized EP Welcome to EP Edge Journal Watch – Issue #5 (January 2026) , your high-yield, evidence-driven electrophysiology podcast designed for practicing EPs who want more than just abstracts. As 2026 begins, electrophysiology is entering a defining phase—where pulsed field ablation (PFA) matures beyond feasibility, device therapy is reframed by competing risk , and “one-size-fits-all” ablation strategies give way to personalization . In this episode, Dr. Niraj Sharma MD FACC FHRS breaks down practice-changing trials, real-world registries, and mechanistic insights that are actively reshaping how we approach atrial fibrillation ablation, ICD decision-making, leadless pacing, and AF progression. What’s covered in this issue: Long-term ICD outcomes in nonischemic cardiomyopathy Why preventing sudden death does not always translate into survival benefit—and how age and competing risk matter. Leadless pacing evolution Dual-chamber leadless pacemakers, operator learning curves, and why high acute atrial thresholds don’t predict chronic failure . Reducing CIED infections How a simple iodinated adhesive drape significantly lowers contamination and infection risk. AF progression as a biologic signal Why device-detected AF progression predicts mortality, heart failure, and stroke risk. Monitoring-driven AF management How implantable cardiac monitors change rhythm-control strategies and outcomes. Pulsed Field Ablation at scale CE-Mark data, IDE trials, and the MANIFEST-US registry defining safety, durability, and workflow in real-world PFA. Rare but serious delayed PFA complications What every electrophysiologist should know about delayed ischemia and malignant arrhythmias…

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