# LAAO vs Anticoagulation Explained: WATCHMAN FLX, AF Ablation Recurrence, Post-TAVR Heart Block & ICU AF, Hormones and TdP – EP Edge Journal Watch

Page: https://stenobird.com/podcast/ep-edge-journal-watch-7561379/laao-vs-anticoagulation-explained-watchman-flx-af-ablation-recurrence-post-tavr-heart-block-icu-af-hormones-and-tdp-ep-edge-journal-watch
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Podcast: [EP Edge Journal Watch](https://stenobird.com/podcast/ep-edge-journal-watch-7561379)
Published: 2026-01-12T10:30:00+00:00
Episode link: https://share.transistor.fm/s/29bb14cf
Audio file: https://media.transistor.fm/29bb14cf/6db2486b.mp3
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JSON: https://stenobird.com/v1/public/podcasts/ep-edge-journal-watch-7561379/episodes/laao-vs-anticoagulation-explained-watchman-flx-af-ablation-recurrence-post-tavr-heart-block-icu-af-hormones-and-tdp-ep-edge-journal-watch
Duration seconds: 856

## Resource

EP Edge Journal Watch Podcast — Issue 6 (January 2026) Left Atrial Appendage Occlusion, AF Ablation Insights, Post-TAVR Conduction, ICU Anticoagulation & Translational EP Signals EP Edge Journal Watch is your high-yield, evidence-driven electrophysiology podcast—designed for busy clinicians who want clinical relevance, mechanistic insight, and practice-changing nuance without wading through every paper. In Issue 6 (January 2026) , we anchor the episode around Left Atrial Appendage Occlusion (LAAO) —examining long-term randomized outcomes, implant mechanics that truly matter, and frontier strategies for the most complex patients—then expand into essential EP topics you’ll actually use on rounds . What’s covered in this episode? 1. LAAO vs Oral Anticoagulation — Long-Term Outcomes We break down a contemporary randomized trial meta-analysis (including OPTION ) examining: Stroke and systemic embolism Hemorrhagic vs non-procedural bleeding A provocative mortality signal favoring LAAO Practical implications for counseling ablation patients and high-bleeding-risk populations. 2. WATCHMAN FLX Mechanics — Why Compression Matters A deep dive into device sizing and compression: Over-compression thresholds Impact on peridevice leak (PDL) How this data should influence real-world implant decisions. 3. Persistent LAA Thrombus — Is There a Salvage Path? We discuss a multicenter experience using: Percutaneous aspiration thrombectomy Embolic protection strategies Same-session, no-touch LAA closure A feasibility signal—not for routine practice, but critical for expert centers facing clinical dead-ends. OPTION Sub-Analysis — Does LAAO Worsen AF Recurrence? Using the largest randomized dataset available: Concomitant vs staged LAAO with ablation AF recurrence, cardioversion, redo ablat…

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