# EP Edge® Journal Watch, Issue 27, June 2026: CT-Guided VT Ablation, PFA Safety, Posterior Wall Isolation, and AF Substrate Precision

Page: https://stenobird.com/podcast/ep-edge-journal-watch-7561379/ep-edge-journal-watch-issue-27-june-2026-ct-guided-vt-ablation-pfa-safety-posterior-wall-isolation-and-af-substrate-precision
Text version: https://stenobird.com/podcast/ep-edge-journal-watch-7561379/ep-edge-journal-watch-issue-27-june-2026-ct-guided-vt-ablation-pfa-safety-posterior-wall-isolation-and-af-substrate-precision.md
Podcast: [EP Edge Journal Watch](https://stenobird.com/podcast/ep-edge-journal-watch-7561379)
Published: 2026-06-29T09:30:00+00:00
Episode link: https://share.transistor.fm/s/dfeebe64
Audio file: https://media.transistor.fm/dfeebe64/21f74752.mp3
Processing state: not_requested
JSON: https://stenobird.com/v1/public/podcasts/ep-edge-journal-watch-7561379/episodes/ep-edge-journal-watch-issue-27-june-2026-ct-guided-vt-ablation-pfa-safety-posterior-wall-isolation-and-af-substrate-precision
Duration seconds: 2918

## Resource

In this episode of EP Edge® Journal Watch , Dr. Sharma reviews the June 2026 Issue 27 newsletter, focusing on a central question in modern cardiac electrophysiology: how do we better match mechanism to intervention? This issue explores smarter procedural targeting, safer energy delivery, functional substrate assessment, and the evolving biology of atrial and ventricular arrhythmias. The episode begins with the InEurHeart trial , a randomized study of CT-guided ventricular tachycardia ablation in ischemic cardiomyopathy. Dr. Sharma explains why preprocedural cardiac CT may help identify scar-related VT isthmuses, shorten procedure time, and create a more reproducible workflow, while also discussing why anatomy alone cannot fully replace functional electroanatomic mapping. The discussion then moves to posterior wall isolation in persistent atrial fibrillation , including a study of very high-output pace-capture testing. The key clinical question is whether more aggressive confirmation of posterior wall inexcitability improves outcomes. The results challenge the assumption that more lesions, more energy, and stricter capture endpoints necessarily produce better rhythm control. Next, the episode examines CTI DEEP mapping , or decrement evoked potentials, as a functional electrophysiology marker for atrial flutter susceptibility in patients undergoing AF ablation. Dr. Sharma explains what DEEP is, how it is measured using extrastimulus pacing from the lateral tricuspid annulus and proximal coronary sinus, and why functional conduction delay may be more informative than CTI anatomy alone. The procedural safety conversation continues with a mechanistic study of left bundle branch area pacing showing that sheath withdrawal may be a vulnerable phase for septal perforation. This…

## Actions

- request_transcript: `POST https://stenobird.com/v1/public/podcasts/ep-edge-journal-watch-7561379/episodes/ep-edge-journal-watch-issue-27-june-2026-ct-guided-vt-ablation-pfa-safety-posterior-wall-isolation-and-af-substrate-precision/transcription-requests` — Idempotently request low-priority transcript generation for this episode.
- read_markdown: `GET https://stenobird.com/podcast/ep-edge-journal-watch-7561379/ep-edge-journal-watch-issue-27-june-2026-ct-guided-vt-ablation-pfa-safety-posterior-wall-isolation-and-af-substrate-precision.md` — Read the agent-friendly Markdown representation of this episode resource.

A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed.

## Transcript

Full transcripts are not published on public pages unless there is a clear rights basis.