# EP-EDGE Journal Watch #7: Direct Oral Anti-Coagulant Adherence, AF Risk Stressors, ns-PFA Safety & EP Device Updates

Page: https://stenobird.com/podcast/ep-edge-journal-watch-7561379/ep-edge-journal-watch-7-direct-oral-anti-coagulant-adherence-af-risk-stressors-ns-pfa-safety-ep-device-updates
Text version: https://stenobird.com/podcast/ep-edge-journal-watch-7561379/ep-edge-journal-watch-7-direct-oral-anti-coagulant-adherence-af-risk-stressors-ns-pfa-safety-ep-device-updates.md
Podcast: [EP Edge Journal Watch](https://stenobird.com/podcast/ep-edge-journal-watch-7561379)
Published: 2026-01-19T10:30:00+00:00
Episode link: https://share.transistor.fm/s/9edd4099
Audio file: https://media.transistor.fm/9edd4099/01cab9ac.mp3
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JSON: https://stenobird.com/v1/public/podcasts/ep-edge-journal-watch-7561379/episodes/ep-edge-journal-watch-7-direct-oral-anti-coagulant-adherence-af-risk-stressors-ns-pfa-safety-ep-device-updates
Duration seconds: 777

## Resource

EP-EDGE Journal Watch – Issue 7 (January 2026) Advanced Cardiac Electrophysiology Podcast | AF, DOACs, PFA, Devices & Heart Failure In EP-EDGE Journal Watch Issue 7 , Dr. Niraj Sharma delivers a high-impact, clinician-focused breakdown of the most practice-changing cardiac electrophysiology studies published in late 2025 and early 2026. This episode moves beyond headlines to translate data into actionable decisions for the EP lab and clinic . Key topics covered in this episode include: • DOAC adherence and stroke risk in atrial fibrillation How many anticoagulant doses can patients truly miss before stroke risk rises sharply? A landmark real-world analysis using machine-learning–optimized adherence modeling challenges the long-standing 80% adherence rule and shows why near-perfect DOAC consistency is required for stroke prevention . • Stressor-associated atrial fibrillation Once considered “reversible,” AF occurring during surgery, sepsis, or myocardial infarction is now shown to carry high recurrence, stroke, heart failure, and mortality risk . This episode explains why reassurance alone is no longer appropriate—and how long-term management should change. • Pulsed-field ablation (PFA) and laryngospasm A newly recognized, high-acuity airway complication associated with PFA under general anesthesia. Learn the proposed mechanisms, anesthesia implications, and how EP labs should adapt airway and neuromuscular blockade strategies. • Nanosecond PFA versus radiofrequency ablation for paroxysmal AF A randomized trial and editorial analysis comparing efficacy, procedural efficiency, fluoroscopy exposure, and safety—shifting the discussion from rhythm success to workflow and radiation trade-offs . • PFAS regulations and electrophysiology devices Why conflating harmful PFAS…

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## Transcript

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