# Ep. 206: Genetics in ALS and frontotemporal dementia – from pathophysiology to treatment Page: https://stenobird.com/podcast/eancast-weekly-neurology-5497158/ep-206-genetics-in-als-and-frontotemporal-dementia-from-pathophysiology-to-treatment Text version: https://stenobird.com/podcast/eancast-weekly-neurology-5497158/ep-206-genetics-in-als-and-frontotemporal-dementia-from-pathophysiology-to-treatment.md Podcast: [eanCast: Weekly Neurology](https://stenobird.com/podcast/eancast-weekly-neurology-5497158) Published: 2026-06-21T22:05:00+00:00 Episode link: https://eancast.podigee.io/206-neue-episode Audio file: https://audio.podigee-cdn.net/2516790-m-0413d9b3f68285c215143eb5d42e0d18.mp3?source=feed Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/eancast-weekly-neurology-5497158/episodes/ep-206-genetics-in-als-and-frontotemporal-dementia-from-pathophysiology-to-treatment Duration seconds: 1194 ## Resource Moderator: Cláudia Santos Silva (Lisbon, Portugal) Guest: Andrea Calvo (Turin, Italy) In this episode, Cláudia Santos Silva speaks with Andrea Calvo about the genetics of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). They discuss the shared genetic basis of these disorders, key disease-associated genes, and the role of genetic testing, counselling, and result interpretation in clinical practice, highlighting how genetic discoveries are advancing precision medicine and emerging gene-targeted therapies in ALS and FTD. ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/eancast-weekly-neurology-5497158/episodes/ep-206-genetics-in-als-and-frontotemporal-dementia-from-pathophysiology-to-treatment/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/eancast-weekly-neurology-5497158/ep-206-genetics-in-als-and-frontotemporal-dementia-from-pathophysiology-to-treatment.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.