# Miscarrage after mRNA vaccine

Page: https://stenobird.com/podcast/dr-john-campbell-7851784/miscarrage-after-mrna-vaccine
Text version: https://stenobird.com/podcast/dr-john-campbell-7851784/miscarrage-after-mrna-vaccine.md
Podcast: [Dr. John Campbell](https://stenobird.com/podcast/dr-john-campbell-7851784)
Published: 2026-07-19T23:30:00+00:00
Episode link: https://traffic.megaphone.fm/VG4549901475.mp3
Audio file: https://traffic.megaphone.fm/VG4549901475.mp3
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JSON: https://stenobird.com/v1/public/podcasts/dr-john-campbell-7851784/episodes/miscarrage-after-mrna-vaccine
Duration seconds: 2559

## Resource

Check out Josh on Substack, https://researchrebel.substack.com/ Observed-to-Expected Fetal Losses Following mRNA COVID-19 Vaccination in Early Pregnancy https://www.medrxiv.org/content/10.1101/2025.06.18.25329352v1 The clinical trials used to approve COVID-19 vaccines excluded pregnant women, and existing safety assessments of COVID-19 vaccination, particularly during early stages of pregnancy, are limited to observational studies prone to various types of potential bias, including healthy vaccinee bias. Methods March 1, 2016 and February 28, 2022 N = 226,395 pregnancies Observed-to-expected comparisons mRNA COVID-19 vaccination, weeks 8-13 and 14-27 Influenza during gestational weeks 8-27 and women vaccinated prior to pregnancy for COVID-19 or influenza, used as controls. Expected number of fetal losses, historical data from 2016-2018 (that incorporates individual-level risk factors) A simulated trial, where each vaccinated pregnant woman included in the cohort was ‘matched’ with a ‘synthetic unvaccinated control’ with similar individual and pregnancy characteristics. Results COVID-19 vaccination with dose 1 during weeks 8-13 Associated with higher-than-expected fetal losses 13 versus 9 expected for every 100 exposed pregnancies 3.85 additional fetal losses above expected per 100 pregnancies Most of the excess fetal losses occurred after gestational week 20, and nearly half occurred after gestational week 25. Women vaccinated with dose 3 during weeks 8-13 A higher-than-expected number of fetal losses Nearly 1.9 additional fetal losses above expected per 100 pregnancies. In contrast, Pregnant women vaccinated for influenza during weeks 8-27 Exhibited a consistently lower-than-expected observed number of fetal losses, likely the result of healthy vaccinee bias. Women va…

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