# Delta Plus, cause for concern?

Page: https://stenobird.com/podcast/dr-john-campbell-7851784/delta-plus-cause-for-concern
Text version: https://stenobird.com/podcast/dr-john-campbell-7851784/delta-plus-cause-for-concern.md
Podcast: [Dr. John Campbell](https://stenobird.com/podcast/dr-john-campbell-7851784)
Published: 2026-09-14T03:10:00+00:00
Episode link: https://traffic.megaphone.fm/VG2274874047.mp3
Audio file: https://traffic.megaphone.fm/VG2274874047.mp3
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JSON: https://stenobird.com/v1/public/podcasts/dr-john-campbell-7851784/episodes/delta-plus-cause-for-concern
Duration seconds: 1560

## Resource

New descendant of the Delta variant, Delta, predominant, 99.8% of sequenced cases in England As of 11 October 2021 Delta, predominant variant, 99.8% of sequenced cases in England Delta sublineage newly designated as AY.4.2 There are also small numbers of new cases of Delta with E484K and Delta with E484Q https://www.gov.uk/government/publications/investigation-of-sars-cov-2-variants-technical-briefings https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1025827/Technical_Briefing_25.pdf https://www.theguardian.com/world/2021/oct/19/fears-grow-in-england-over-rise-of-new-covid-delta-variant https://www.thesun.co.uk/health/16463658/new-delta-subvariant-uk-more-infectious/ https://www.italy24news.com/News/164491.html https://www.msn.com/en-us/health/medical/delta-ay-sub-variant-which-requires-urgent-research-found-in-these-us-states/ar-AAPFk3S https://www.bbc.co.uk/news/health-58965650 UK genetic sequencing, 6%, now 8% or more UK, over a million sequences performed so far On an increasing trajectory US, Denmark, Canada US, 3 cases sequenced, no clusters reported North Carolina, California, DC 10 cases in Israel, all from US UK, 14,247 sequenced as of Monday, October 18th AY.4.2, Delta Plus, Spike protein change (AY means it is a delta subtype) (AY.4 is already 80% in the UK) Mutations - Y145H and A222V Found in various lineages since the beginning of the pandemic Will this give the virus additional powers? Vaccine escape? Slight effect on the binding between antibodies and the virus Not yet a variant of concern or variant under investigation WHO, next few days, nu variant Original Delta, classified as VOC, UK May 2021 July 2021 experts identified AY.4.2. Sublineage of Delta, increasing slowly since then Prof Francois Balloux, Un…

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## Transcript

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