# Theory of Change: #1: How Alexander Berger weighs the world’s biggest problems Page: https://stenobird.com/podcast/devex-podcasts-65118/theory-of-change-1-how-alexander-berger-weighs-the-world-s-biggest-problems Text version: https://stenobird.com/podcast/devex-podcasts-65118/theory-of-change-1-how-alexander-berger-weighs-the-world-s-biggest-problems.md Podcast: [Devex Podcasts](https://stenobird.com/podcast/devex-podcasts-65118) Published: 2026-06-02T16:56:00+00:00 Episode link: https://soundcloud.com/devex-intl/how-alexander-berger-weighs-the-world-s-biggest-problems Audio file: https://feeds.soundcloud.com/stream/2332141802-devex-intl-how-alexander-berger-weighs-the-world-s-biggest-problems.mp3 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/devex-podcasts-65118/episodes/theory-of-change-1-how-alexander-berger-weighs-the-world-s-biggest-problems Duration seconds: 3988 ## Resource Coefficient Giving, one of the world’s largest effective-giving funders, is about to go even bigger. On the heels of its biggest funding year ever in 2025 — in which it channeled over $1 billion to highest-impact causes — the organization formerly known as Open Philanthropy and funded by Facebook cofounder Dustin Moskovitz and his wife Cari Tuna is eyeing annual growth upward of 50% and bringing on more staff to get it done. The person behind that vision is Alexander Berger, Coefficient Giving’s cofounder and CEO. Berger is in charge of turning Facebook wealth — and, increasingly, funds from other donors — into as many lives saved and improved as possible. The organization is a major funder in global health and development, catastrophic risk, research and innovation, and even farm animal welfare. Last week, Coefficient Giving launched a new pooled fund to tackle Group A Streptococcus — an easily treated disease that is still responsible for nearly 700,000 deaths a year — a cause that reflects the organization’s framework for tackling problems that are important, neglected, and tractable. In a rare, in-depth interview with Devex Senior Reporter Michael Igoe, Berger sheds light on Coefficient Giving’s rapid growth plans, its strategy for choosing high-impact causes, the rise of artificial intelligence philanthropy, and his own approach to affecting change in an uncertain world. This is the first episode of Theory of Change, a new podcast series from Devex featuring candid interviews with leaders shaping the future of global development. ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/devex-podcasts-65118/episodes/theory-of-change-1-how-alexander-berger-weighs-the-world-s-biggest-problems/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/devex-podcasts-65118/theory-of-change-1-how-alexander-berger-weighs-the-world-s-biggest-problems.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.