# Patient-Centered Management of CDK4/6 Inhibitor Therapy: Adverse Event Mitigation, Adherence, and Persistence in HR+/HER2- Breast Cancer

Page: https://stenobird.com/podcast/decera-clinical-education-oncology-podcast-1302999/patient-centered-management-of-cdk4-6-inhibitor-therapy-adverse-event-mitigation-adherence-and-persistence-in-hr-her2-breast-cancer
Text version: https://stenobird.com/podcast/decera-clinical-education-oncology-podcast-1302999/patient-centered-management-of-cdk4-6-inhibitor-therapy-adverse-event-mitigation-adherence-and-persistence-in-hr-her2-breast-cancer.md
Podcast: [Decera Clinical Education Oncology Podcast](https://stenobird.com/podcast/decera-clinical-education-oncology-podcast-1302999)
Published: 2026-04-14T19:56:16+00:00
Episode link: https://oncologypodcast.simplecast.com/episodes/patient-centered-management-of-cdk4-6-inhibitor-therapy-adverse-event-mitigation-adherence-and-persistence-in-hr-her2-breast-cancer-pCssUC_H
Audio file: https://afp-928689-injected.calisto.simplecastaudio.com/1d8e143b-904e-45be-b6c5-8fba793d9d74/episodes/3cf5ff3c-6ce7-45dd-978c-9331c8089697/audio/128/default.mp3?aid=rss_feed&awCollectionId=1d8e143b-904e-45be-b6c5-8fba793d9d74&awEpisodeId=3cf5ff3c-6ce7-45dd-978c-9331c8089697&feed=GlfUTtJq
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Duration seconds: 2686

## Resource

In this episode, experts discuss practical, patient-centered strategies for CDK4/6 inhibitor therapy in HR-positive/HER2-negative breast cancer, with a focus on adverse event monitoring and management, dose modifications, adherence support, and preventing early discontinuation. The discussion also highlights real-world approaches to counseling, multidisciplinary coordination, and helping patients stay on therapy long term.

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