# #202 Dementia Part 2: Gray Matters Segment Page: https://stenobird.com/podcast/core-im-internal-medicine-podcast-60389/202-dementia-part-2-gray-matters-segment Text version: https://stenobird.com/podcast/core-im-internal-medicine-podcast-60389/202-dementia-part-2-gray-matters-segment.md Podcast: [Core IM | Internal Medicine Podcast](https://stenobird.com/podcast/core-im-internal-medicine-podcast-60389) Published: 2026-03-12T08:22:24+00:00 Episode link: https://www.coreimpodcast.com/2026/03/12/dementia-part-2-gray-matters-segment/ Audio file: https://pscrb.fm/rss/p/audio2.redcircle.com/episodes/3ff397d6-8f21-42cf-9368-c2780a0fd4c3/stream.mp3 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/core-im-internal-medicine-podcast-60389/episodes/202-dementia-part-2-gray-matters-segment Duration seconds: 2836 ## Resource Most clinicians see dementia medications on the med rec, but many of us aren’t sure how much they actually help . In this episode we break down donepezil, memantine, and the new anti-amyloid drugs, and when to stop them. • Do cholinesterase inhibitors really work? • What should clinicians know about lecanemab and donanemab before referring patients? • How much benefit should we expect and for how long? • When should you deprescribe dementia medications ? 🔹 Sponsor: Caraway’s cookware set is a favorite for a reason. For 10% off, go to Carawayhome.com/ CoreIM or use code CoreIM at checkout. 🔹 Transcript and Shownotes 02:27 | Deep Dive 1: How do we deliver the news of a diagnosis of dementia? 09:41 | Deep Dive 2: Prescribing medications for cognitive decline 29:30 | Deep Dive 3: Patient-centered management for a patient with cognitive decline 35:46 | Deep Dive 4: Planning for an uncertain future Tags: CoreIM, Internal Medicine, Medical Education, Cognitive Screening, primary care, nurse practitioner, physician assistant Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Advertising Inquiries: https://redcircle.com/brands Privacy & Opt-Out: https://redcircle.com/privacy ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/core-im-internal-medicine-podcast-60389/episodes/202-dementia-part-2-gray-matters-segment/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/core-im-internal-medicine-podcast-60389/202-dementia-part-2-gray-matters-segment.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.