# #483 - The Paradox of the Organism: A Dialogue with Arvid Ågren & Manus Patten Page: https://stenobird.com/podcast/converging-dialogues-1498806/483-the-paradox-of-the-organism-a-dialogue-with-arvid-gren-manus-patten Text version: https://stenobird.com/podcast/converging-dialogues-1498806/483-the-paradox-of-the-organism-a-dialogue-with-arvid-gren-manus-patten.md Podcast: [Converging Dialogues](https://stenobird.com/podcast/converging-dialogues-1498806) Published: 2026-03-18T22:00:00+00:00 Episode link: https://convergingdialogues.substack.com/p/483-the-paradox-of-the-organism-a Audio file: https://api.substack.com/feed/podcast/189520031/b4571f93926dfeb83064aeaccdf5b11c.mp3 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/converging-dialogues-1498806/episodes/483-the-paradox-of-the-organism-a-dialogue-with-arvid-gren-manus-patten Duration seconds: 4139 ## Resource In this episode, Xavier Bonilla has a dialogue with Arvid Ågren and Manus Patten about internal conflicts within organisms. They provide an overview of the paradox of the organism, clinical examples of cancer and pregnancy, direct, indirect, and inclusive fitness. They talk about cooperation within an organism, conflict, transmission and trait distorters, price equation, conflict awareness, neo-Darwinian embryology, biology of selfhood, and many more topics. J. Arvid Ågren is Assistant Professor at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University and Affiliated Researcher at the Evolutionary Biology Centre at Uppsala University. He is the author of The Gene’s-Eye View of Evolution . Manus M. Patten is an evolutionary biologist whose research explores the consequences of conflict, both for organisms and for evolutionary theory. He is Teaching Professor in Biology at Georgetown University. They are co-editors of the book, The Paradox of the Organism: Adaptation and Internal Conflict . Get full access to Converging Dialogues at convergingdialogues.substack.com/subscribe ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/converging-dialogues-1498806/episodes/483-the-paradox-of-the-organism-a-dialogue-with-arvid-gren-manus-patten/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/converging-dialogues-1498806/483-the-paradox-of-the-organism-a-dialogue-with-arvid-gren-manus-patten.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.