# Episode 59: The Future of Ion Chromatography | PFAS Testing, EPA 1621 & AOF Explained #analyticalchemistry Page: https://stenobird.com/podcast/concentrating-on-chromatography-7157959/episode-59-the-future-of-ion-chromatography-pfas-testing-epa-1621-aof-explained-analyticalchemistry Text version: https://stenobird.com/podcast/concentrating-on-chromatography-7157959/episode-59-the-future-of-ion-chromatography-pfas-testing-epa-1621-aof-explained-analyticalchemistry.md Podcast: [Concentrating on Chromatography](https://stenobird.com/podcast/concentrating-on-chromatography-7157959) Published: 2026-05-04T10:00:00+00:00 Episode link: https://podcasters.spotify.com/pod/show/chromatography/episodes/Episode-59-The-Future-of-Ion-Chromatography--PFAS-Testing--EPA-1621--AOF-Explained-analyticalchemistry-e3ifqv7 Audio file: https://anchor.fm/s/fd632380/podcast/play/119056807/https%3A%2F%2Fd3ctxlq1ktw2nl.cloudfront.net%2Fstaging%2F2026-3-26%2F422884996-44100-2-6d535364715fe.m4a Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/concentrating-on-chromatography-7157959/episodes/episode-59-the-future-of-ion-chromatography-pfas-testing-epa-1621-aof-explained-analyticalchemistry Duration seconds: 1815 ## Resource How are PFAS regulations changing, and what role will ion chromatography play in the future of environmental testing?In this episode of @ChromatographyTalk , David interviews Jay Gandhi, PhD, Vertical Markets Manager at Metrohm USA, for an in-depth discussion on PFAS analysis, the rise of AOF (Adsorbable Organic Fluorine) testing, and the development of EPA 1621 and ISO 18127 standards.With more than 30 years of experience in ion chromatography, Jay shares valuable perspective on how the field has evolved—from early applications and NASA water recovery projects to today’s challenges involving PFAS, TFA, and emerging contaminants.Topics covered in this episode include:• What PFAS are and why they matter• The difference between targeted PFAS methods and AOF analysis• How combustion ion chromatography works• Behind the scenes of EPA 1621 and ISO 18127 method development• Regulatory trends in water, textiles, and food packaging• TFA analysis using IC-MS and IC-MS/MS• The future of ion chromatography in environmental labsWhether you work in analytical chemistry, environmental testing, water analysis, or chromatography, this episode offers timely insights from one of the industry’s leading experts.Subscribe for more interviews with scientists, researchers, and industry leaders.#PFAS #Chromatography #IonChromatography #EnvironmentalTesting #Metrohm #AnalyticalChemistry #MassSpectrometry #EPA ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/concentrating-on-chromatography-7157959/episodes/episode-59-the-future-of-ion-chromatography-pfas-testing-epa-1621-aof-explained-analyticalchemistry/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/concentrating-on-chromatography-7157959/episode-59-the-future-of-ion-chromatography-pfas-testing-epa-1621-aof-explained-analyticalchemistry.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.