# We should stop burning pharma trials’ lab notes, with Ruxandra Teslo

Page: https://stenobird.com/podcast/complex-systems-with-patrick-mckenzie-patio11-6944962/we-should-stop-burning-pharma-trials-lab-notes-with-ruxandra-teslo
Text version: https://stenobird.com/podcast/complex-systems-with-patrick-mckenzie-patio11-6944962/we-should-stop-burning-pharma-trials-lab-notes-with-ruxandra-teslo.md
Podcast: [Complex Systems with Patrick McKenzie (patio11)](https://stenobird.com/podcast/complex-systems-with-patrick-mckenzie-patio11-6944962)
Published: 2026-01-22T08:00:00+00:00
Episode link: https://www.complexsystemspodcast.com/ruxandra-teslo/
Audio file: https://pscrb.fm/rss/p/prfx.byspotify.com/e/media.transistor.fm/2682a780/73a21128.mp3
Processing state: not_requested
JSON: https://stenobird.com/v1/public/podcasts/complex-systems-with-patrick-mckenzie-patio11-6944962/episodes/we-should-stop-burning-pharma-trials-lab-notes-with-ruxandra-teslo
Duration seconds: 4641

## Resource

Patrick McKenzie (patio11) is joined by Ruxandra Teslo to discuss why drug development keeps getting more expensive despite revolutionary new treatment modalities from GLP-1 agonists to gene therapies. They discuss Eroom’s Law (Moore’s Law in reverse) and Ruxandra's Common Technical Document Project, which aims to build the "Stack Overflow of clinical development" by making regulatory submissions publicly accessible. This will fill a present hole in the education of researchers, lower barriers for small biotechs, and accelerate drug discovery. – Full transcript available here: https://www.complexsystemspodcast.com/ruxandra-teslo/ – Sponsor: Framer Building and maintaining marketing websites shouldn’t slow down your engineers. Framer gives design and marketing teams an all-in-one platform to ship landing pages, microsites, or full site redesigns instantly—without engineering bottlenecks. Get 30% off Framer Pro at framer.com/complexsystems . – Links: Eroom's Law (original paper): https://www.nature.com/articles/nrd3681 Ruxandra’s writing: https://www.writingruxandrabio.com/ Ross Rheingans-Yoo on drug development: https://open.spotify.com/episode/4GiO0KYqxJNCIdltCyhN6m?si=2znQniZ3RXKuX8keNcwWtw Ben Reinhardt on science and development: https://open.spotify.com/episode/0GHegWgLSubYxvATmbWhQu?si=pVCJVITYTqaq65BiST2d0Q – Timestamps: (00:00) Intro (00:56) Challenges in biopharma productivity (03:12) Understanding clinical development (04:59) The role of basic science in drug development (07:39) Clinical development process explained (09:25) Issues in clinical trials and development (19:33) The role of information in clinical trials (20:30) Sponsor: Framer (21:42) The role of information in clinical trials (continued) (32:55) Proposed solutions for clinical development (40:31)…

## Actions

- request_transcript: `POST https://stenobird.com/v1/public/podcasts/complex-systems-with-patrick-mckenzie-patio11-6944962/episodes/we-should-stop-burning-pharma-trials-lab-notes-with-ruxandra-teslo/transcription-requests` — Idempotently request low-priority transcript generation for this episode.
- read_markdown: `GET https://stenobird.com/podcast/complex-systems-with-patrick-mckenzie-patio11-6944962/we-should-stop-burning-pharma-trials-lab-notes-with-ruxandra-teslo.md` — Read the agent-friendly Markdown representation of this episode resource.

A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed.

## Transcript

Full transcripts are not published on public pages unless there is a clear rights basis.