# Chapter Seventeen: Introduction to Simple and Mixed Acid-Base Disorders

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Text version: https://stenobird.com/podcast/channel-your-enthusiasm-1374325/chapter-seventeen-introduction-to-simple-and-mixed-acid-base-disorders.md
Podcast: [Channel Your Enthusiasm](https://stenobird.com/podcast/channel-your-enthusiasm-1374325)
Published: 2025-02-21T15:20:12+00:00
Episode link: http://www.rosebook.club/episodes/2025/2/21/chapter-seventeen
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## Resource

References I said I used MDCalc but I was mistaken I use MedCalX which is nice but getting dated.  We talked about this out of print book that we love: Cohen, J. J., Kassirer, J. P. (1982). Acid-base. United States: Little, Brown. Josh mentioned this article that looked at over 17,000 samples with simultaneous measured and calculated bicarbonate and found a very small difference. Comparison of Measured and Calculated Bicarbonate Values | Clinical Chemistry | Oxford Academic Base deficit or excess- Diagnostic Use of Base Excess in Acid–Base Disorders | NEJM (check out the accompanying letter to the editor from Melanie challenging this article! Along with colleagues Lecker and Zeidel Diagnostic Use of Base Excess in Acid-Base Disorders ) Melanie loves this paper which shows a nice correlation between arterial and venous pH but the rest of the comparisons are disappointing - Comparison of arterial and venous pH, bicarbonate, Pco2 and Po2 in initial emergency department assessment - PMC A nomogram for the interpretation of acid-base data is figure 17-1 in the book, this manuscript with the ! in the conclusion creates the acid-base map.  We debated about whether we like Winter’s formula: Quantitative displacement of acid-base equilibrium in metabolic acidosis (melanie does b/c it used real patients).  Amy’s Voice of God on Dietary Acid Load Review of dietary acid load: https://pubmed.ncbi.nlm.nih.gov/23439373/ , https://pubmed.ncbi.nlm.nih.gov/38282081/ , https://pubmed.ncbi.nlm.nih.gov/33075387/ Survey data from kidney stone formers regarding sources of dietary acid load: https://pubmed.ncbi.nlm.nih.gov/35752401/ Urine profile for vegans and omnivories (urine pH and cations/anions): https://pubmed.ncbi.nlm.nih.gov/36364731/ SWAP-MEAT pilot trial: https://pub…

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