# Episode 154: Is Seed Based Cultivation the Future of Cannabis? - with Dr. Matthew Indest

Page: https://stenobird.com/podcast/cannabis-cultivation-and-science-podcast-224812/episode-154-is-seed-based-cultivation-the-future-of-cannabis-with-dr-matthew-indest
Text version: https://stenobird.com/podcast/cannabis-cultivation-and-science-podcast-224812/episode-154-is-seed-based-cultivation-the-future-of-cannabis-with-dr-matthew-indest.md
Podcast: [Cannabis Cultivation and Science Podcast](https://stenobird.com/podcast/cannabis-cultivation-and-science-podcast-224812)
Published: 2025-12-10T21:17:20+00:00
Episode link: https://www.kisorganics.com/pages/podcast
Audio file: https://afp-901980-injected.calisto.simplecastaudio.com/eb565bbc-b99d-4ea2-a59e-7c4a2ca16b15/episodes/4ed2eb4a-16e2-4f7e-b120-f27b32a1fe1b/audio/128/default.mp3?aid=rss_feed&awCollectionId=eb565bbc-b99d-4ea2-a59e-7c4a2ca16b15&awEpisodeId=4ed2eb4a-16e2-4f7e-b120-f27b32a1fe1b&feed=WsEnHj2A
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Duration seconds: 5151

## Resource

Seed-grown cannabis has been talked about for years, but most commercial growers still lean on clones for consistency. In this episode, Dr. Matthew Indest and I dig into whether the industry is finally approaching a true shift. We unpack the science, the barriers, and the practical realities: genetic stability, uniformity, agronomic traits, pathogen concerns, breeding strategies, and the economics behind large-scale seed adoption. Dr. Indest brings a rare mix of rigorous plant science and real-world cannabis experience. If you’ve wondered whether seed-based cultivation can match or even outperform clonal systems — or what breeders actually need to deliver for that future to happen — this episode lays it out clearly.

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## Transcript

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