# HR-Positive Metastatic Breast Cancer — A Discussion and Debate on First- and Second-Line Therapy Page: https://stenobird.com/podcast/breast-cancer-update-757579/hr-positive-metastatic-breast-cancer-a-discussion-and-debate-on-first-and-second-line-therapy Text version: https://stenobird.com/podcast/breast-cancer-update-757579/hr-positive-metastatic-breast-cancer-a-discussion-and-debate-on-first-and-second-line-therapy.md Podcast: [Breast Cancer Update](https://stenobird.com/podcast/breast-cancer-update-757579) Published: 2026-06-11T17:00:00+00:00 Episode link: https://breast-oncology.captivate.fm/episode/5904-cochrposmbc2025 Audio file: https://dts.podtrac.com/redirect.mp3/episodes.captivate.fm/episode/466caaa5-95c5-4277-b4e7-8354452eb045.mp3 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/breast-cancer-update-757579/episodes/hr-positive-metastatic-breast-cancer-a-discussion-and-debate-on-first-and-second-line-therapy Duration seconds: 3502 ## Resource Dr Sara A Hurvitz from the Fred Hutchinson Cancer Center in Seattle, Washington, and Dr Virginia Kaklamani from the UT Health San Antonio MD Anderson Cancer Center in San Antonio, Texas, discuss patient cases and review relevant data on the management of ER-positive, HER2-negative metastatic breast cancer. CME information and select publications ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/breast-cancer-update-757579/episodes/hr-positive-metastatic-breast-cancer-a-discussion-and-debate-on-first-and-second-line-therapy/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/breast-cancer-update-757579/hr-positive-metastatic-breast-cancer-a-discussion-and-debate-on-first-and-second-line-therapy.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.