# For Oncology Nurses: Oral Selective Estrogen Receptor Degraders in Breast Cancer — Proceedings from the 2026 Annual ONS Congress

Page: https://stenobird.com/podcast/breast-cancer-update-757579/for-oncology-nurses-oral-selective-estrogen-receptor-degraders-in-breast-cancer-proceedings-from-the-2026-annual-ons-congress
Text version: https://stenobird.com/podcast/breast-cancer-update-757579/for-oncology-nurses-oral-selective-estrogen-receptor-degraders-in-breast-cancer-proceedings-from-the-2026-annual-ons-congress.md
Podcast: [Breast Cancer Update](https://stenobird.com/podcast/breast-cancer-update-757579)
Published: 2026-08-18T16:00:00+00:00
Episode link: https://breast-oncology.captivate.fm/episode/6100-ons2026-oralserdsbreast
Audio file: https://dts.podtrac.com/redirect.mp3/episodes.captivate.fm/episode/db3da0a1-a5a2-4029-a22a-05213b6f0265.mp3
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Duration seconds: 5087

## Resource

Featuring perspectives from Ms Blanca Ledezma, Dr Marissa Marti-Smith, Dr Heather McArthur and Dr Ruth M O'Regan, moderated by Dr McArthur, including the following topics: Introduction (0:00) Current Clinical Role of Oral Selective Estrogen Receptor Degraders (SERDs) in HR-Positive Metastatic Breast Cancer (3:37) Practical Considerations with Oral SERDs (15:42) Potential Role of Combination Approaches with Oral SERDs (26:31) Gastrointestinal Adverse Events Documented with Oral SERDs (38:17) Potential Role of Early Therapeutic Switching After Detection of an Emergent ESR1 Mutation (46:51) Other Class-Effect Toxicities Associated with Oral SERDs (1:00:53) Emerging Utility of Adjuvant Oral SERDs (1:10:16) Unique Toxicities Associated with 1 or More Oral SERDs (1:19:17) CME information and select publications

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